TGFBR2 Antibody| F41742-0.08ML/F41742-0.4ML/R30965

TGFBR2 Antibody| F41742-0.08ML/F41742-0.4ML/R30965 | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: N/A

Application: WB, IHC, IF, ELISA

Application Details: Western blot: 1:1000-2000, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50

Application Note: Titration of the TGFBR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TGFBR2 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 13-40 from the human protein was used as the immunogen for this TGFBR2 antibody.

Storage: Aliquot the TGFBR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A