TGFBR3 Antibody | 13-224

TGFBR3 Antibody | 13-224 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-340 of human TGFBR3 (NP_003234.2) .

Research Area: Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Stem Cell

Tested Application: WB, IF

Application: WB: 1:500 - 1:1000
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: SH-SY5Y

Positive Control 2: Mouse brain

Positive Control 3: Mouse lung

Positive Control 4: Rat brain

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 110kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: TGFBR3, transforming growth factor, beta receptor III, BGCAN, betaglycan, betaglycan proteoglycan

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This locus encodes the transforming growth factor (TGF) -beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.