Description
TGFBR3 Antibody | 13-224 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-340 of human TGFBR3 (NP_003234.2) .
Research Area: Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Stem Cell
Tested Application: WB, IF
Application: WB: 1:500 - 1:1000
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: SH-SY5Y
Positive Control 2: Mouse brain
Positive Control 3: Mouse lung
Positive Control 4: Rat brain
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 110kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: TGFBR3, transforming growth factor, beta receptor III, BGCAN, betaglycan, betaglycan proteoglycan
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This locus encodes the transforming growth factor (TGF) -beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.