TLR8 Antibody| F43434-0.08ML/F43434-0.4ML/R30824

TLR8 Antibody| F43434-0.08ML/F43434-0.4ML/R30824 | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the anti-TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This anti-TLR8 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 434-463 from the human protein was used as the immunogen for this anti-TLR8 antibody.

Storage: Aliquot the anti-TLR8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A