TLR9 Antibody| F43195-0.08ML/F43195-0.4ML/N1014-100UG/N1014-25UG

TLR9 Antibody| F43195-0.08ML/F43195-0.4ML/N1014-100UG/N1014-25UG | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, FACS, ELISA

Application Details: Western blot: 1:1000, Flow Cytometry: 1:10-1:50

Application Note: Titration of the TLR9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TLR9 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 842-870 from the human protein was used as the immunogen for this TLR9 antibody.

Storage: Aliquot the TLR9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A