TNK2 Polyclonal Antibody | E-AB-12226

TNK2 Polyclonal Antibody | E-AB-12226 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Acetate kinase 1, Acetokinase 1, ACK 1, ACK, ACK-1, ACK1, ACK1, Activated Cdc42 associated kinase 1, Activated CDC42 kinase 1, Activated p21cdc42Hs kinase, FLJ44758, FLJ45547, p21cdc42Hs, TNK 2, TNK2, Tyrosine kinase non receptor 2, Tyrosine kinase non receptor protein 2, Tyrosine kinase non-receptor protein 2

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human TNK2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 119 kDa

Molecular Weight(Observed): N/A