Description
TNK2 Polyclonal Antibody | E-AB-12226 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Acetate kinase 1, Acetokinase 1, ACK 1, ACK, ACK-1, ACK1, ACK1, Activated Cdc42 associated kinase 1, Activated CDC42 kinase 1, Activated p21cdc42Hs kinase, FLJ44758, FLJ45547, p21cdc42Hs, TNK 2, TNK2, Tyrosine kinase non receptor 2, Tyrosine kinase non receptor protein 2, Tyrosine kinase non-receptor protein 2
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Background: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human TNK2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 119 kDa
Molecular Weight(Observed): N/A