TOFA | B2167

TOFA is an allosteric inhibitor of acetyl Co-A carboxylase (ACC1). TOFA blocks fatty acid synthesis and Induces apoptosis in a dose-dependent manner. Stimulates neurite outgrowth and neuronal differentiation in rat pheochromocytoma cells. TOFA impairs glucose-stimulated insulin secretion after chronic treatment.

TOFA is an allosteric inhibitor of acetyl Co-A carboxylase (ACC1). TOFA blocks fatty acid synthesis and Induces apoptosis in a dose-dependent manner. Stimulates neurite outgrowth and neuronal differentiation in rat pheochromocytoma cells. TOFA impairs glucose-stimulated insulin secretion after chronic treatment.

B2167 | TOFA DataSheet

Alternate Name/Synonyms: 5-(tetradecyloxy)-2-furancarboxylic acid; RM14514

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 54857-86-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₃₂O₄

Molecular Weight: 324.5

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (~2 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An allosteric acetyl Co-A carboxylase (ACC1) inhibitor

MDL Number: NFCD01726059

PubChem CID: 115175

SMILES: CCCCCCCCCCCCCCOC1=CC=C(O1)C(=O)O

InChi: InChI=1S/C19H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22-18-15-14-17(23-18)19(20)21/h14-15H,2-13,16H2,1H3,(H,20,21)

InChi Key: CZRCFAOMWRAFIC-UHFFFAOYSA-N