TOR2A Antibody| F40020-0.08ML/F40020-0.4ML

TOR2A Antibody| F40020-0.08ML/F40020-0.4ML | Gentaur UK, US & Europe Distribution

Background: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Rat

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the TOR2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TOR2A antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 194-221 from the human protein was used as the immunogen for this TOR2A antibody.

Storage: Aliquot the TOR2A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A