Transthyretin Antibody | XW-7686

Transthyretin Antibody | XW-7686 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human

Homology: N/A

Immunogen: 1-147

Research Area: Other

Tested Application: E, WB

Application: Transthyretin antibody can be used for the detection of Transthyretin by ELISA and Western Blot, may also work for ICC and IHC.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 15.9 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: Transthyretin antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: PALB, Transthyretin, ATTR, CTS, CTS1, PALB, TBPA, HEL111, HsT2651, TTR, Prealbumin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

DISEASE: Defects in TTR are a cause of hyperthyroxinemia [MIM:176300].

SUBUNIT: Homotetramer.

SIMILARITY: Belongs to the transthyretin family.

SUBCELLULAR LOCATION: Secreted protein.

TISSUE SPECIFICITY: Most abundant in the choroid plexus. Also present in the liver.

DOMAIN: Each monomer has two 4-stranded β sheets and the shape of a prolate ellipsoid. Antiparallel β-sheet interactions link monomers into dimers. A short loop from each monomer forms the main dimer-dimer interaction. These two pairs of loops separate the opposed, convex β-sheets of the dimers to form an internal channel.