TREM2, human recombinant | 7357

TREM2 is a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The protein functions in immune response and maybe involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. Recombinant human TREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

7357 | TREM2 human recombinant DataSheet

Biomolecule/Target: TREM2

Synonyms: Triggering receptor expressed on myeloid cells 2, Trem2a, Trem2b, Trem2c

Alternates names: Triggering receptor expressed on myeloid cells 2, Trem2a, Trem2b, Trem2c

Taglines: Involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines

NCBI Gene ID #: 10850

NCBI Gene Symbol: CCL27

Gene Source: Human

Accession #: Q9Y4X3

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 20.4 kDa (181 aa, 19-161 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 0.25 mg/ml

Appearance: Liquid

Physical form description: 0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 1 mM DTT and 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MFLLPPSTAC CTQLYRKPLS DKLLRKVIQV ELQEADGDCH LQAFVLHLAQ RSICIHPQNP SLSQWFEHQE RKLHGTLPKL NFGMLRKMG.