BW
TXNIP polyclonal Antibody | BS91389
- SKU:
- BW-BS91389
- Availability:
- Usually ships in 5 working days
Description
TXNIP polyclonal Antibody | BS91389 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC FC
Application Range: WB:1:1000-1:5,000 ICC/IF:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: TXNIP polyclonal Antibody detects endogenous levels of TXNIP protein.
Molecular Weight: 44 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TXNIP, VDUP1, EST01027, HHCPA78, THIF, Thioredoxin binding protein 2, Thioredoxin interacting protein, Thioredoxin-binding protein 2, Thioredoxin-interacting protein, TXNIP, TXNIP, Upregulated by 1, 25 dihydroxyvitamin D 3, VDUP1, Vitamin D3 up-regulated protein 1,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: