TXNIP polyclonal Antibody | BS91389

TXNIP polyclonal Antibody | BS91389 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IHC FC

Application Range: WB:1:1000-1:5,000 ICC/IF:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TXNIP polyclonal Antibody detects endogenous levels of TXNIP protein.

Molecular Weight: 44 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TXNIP, VDUP1, EST01027, HHCPA78, THIF, Thioredoxin binding protein 2, Thioredoxin interacting protein, Thioredoxin-binding protein 2, Thioredoxin-interacting protein, TXNIP, TXNIP, Upregulated by 1, 25 dihydroxyvitamin D 3, VDUP1, Vitamin D3 up-regulated protein 1,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: