UBF Antibody (UBF1)| F42275-0.4ML

UBF Antibody (UBF1)| F42275-0.4ML | Gentaur UK, US & Europe Distribution

Background: Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human. UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the UBF antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This UBF antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 631-660 from the human protein was used as the immunogen for this UBF1 / UBF antibody.

Storage: Aliquot the UBF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A