UNC13D polyclonal Antibody | BS72432

UNC13D polyclonal Antibody | BS72432 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB 1:1000 - 1:2000

Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: UNC13D polyclonal Antibody detects endogenous levels of UNC13D protein.

Molecular Weight: ~ 128 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FHL3;HLH3;HPLH3;Munc13-4

Immunogen: Recombinant protein of human UNC13D

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: