BW
UNC13D polyclonal Antibody | BS72432
- SKU:
- BW-BS72432
- Availability:
- Usually ships in 5 working days
Description
UNC13D polyclonal Antibody | BS72432 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB 1:1000 - 1:2000
Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: UNC13D polyclonal Antibody detects endogenous levels of UNC13D protein.
Molecular Weight: ~ 128 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FHL3;HLH3;HPLH3;Munc13-4
Immunogen: Recombinant protein of human UNC13D
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: