Vicriviroc Malate | 1599

Second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC₅₀ =0.46 nM and IC₉₀ =1~10 nM to HIV isolates (n=52).

Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC₅₀ =0.46 nM and IC₉₀ =1~10 nM to HIV isolates (n=52).

1599 | Vicriviroc Malate DataSheet

Alternate Name/Synonyms: Vicriviroc Maleate, SCH 417690, SCH-D

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 541503-81-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₃₈F₃N₅O₂.C₄H₆O₅

Molecular Weight: 667.72

Cell-Permeable?: Yes

Purity: ≥99%

Solubilities: H₂O

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A CCR5 antagonist

MDL Number: MFCD00466380

PubChem CID: 10218922

SMILES: CC1CN(CCN1C(COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(C(C(=O)O)O)C(=O)O

InChi: InChI=1S/C28H38F3N5O2.C4H6O5/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8- 23(9-7-22)28(29, 30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3;5-2(4(8)9)1- 3(6)7/h6-9,18-19,24H,10-17H2,1-5H3;2,5H,1H2,(H,6,7)(H,8,9)/t19-, 24-;/m0./s1

InChi Key: HQJIGHNTROUVLT-RIAYWLAYSA-N