Description
Second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC₅₀ =0.46 nM and IC₉₀ =1~10 nM to HIV isolates (n=52).
Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC₅₀ =0.46 nM and IC₉₀ =1~10 nM to HIV isolates (n=52).
1599 | Vicriviroc Malate DataSheet
Alternate Name/Synonyms: Vicriviroc Maleate, SCH 417690, SCH-D
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 541503-81-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₈H₃₈F₃N₅O₂.C₄H₆O₅
Molecular Weight: 667.72
Cell-Permeable?: Yes
Purity: ≥99%
Solubilities: H₂O
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A CCR5 antagonist
MDL Number: MFCD00466380
PubChem CID: 10218922
SMILES: CC1CN(CCN1C(COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(C(C(=O)O)O)C(=O)O
InChi: InChI=1S/C28H38F3N5O2.C4H6O5/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8- 23(9-7-22)28(29, 30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3;5-2(4(8)9)1- 3(6)7/h6-9,18-19,24H,10-17H2,1-5H3;2,5H,1H2,(H,6,7)(H,8,9)/t19-, 24-;/m0./s1
InChi Key: HQJIGHNTROUVLT-RIAYWLAYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
RT |
Shelf Life: |
24months |