Description
Zebularine is a potent inhibitor of cytidine deaminase and DNA methylation; inhjbits DNA methylation by forming a covalent complex with DNA methyltransferases (DNMTs). Displays antitumor properties.
Zebularine is a potent inhibitor of cytidine deaminase and DNA methylation.
Alternate Name/Synonyms: 1H-β-D-ribofuranosyl-2-pyrimidinone; NSC 309132
Appearance: White solid
Formulation: N/A
CAS Number: 3690-10-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₉H₁₂N₂O₅
Molecular Weight: 228.2
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (100 mM) or H2O (100 mM)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A DNA methylation inhibitor
MDL Number: MFCD04973699
PubChem CID: 100016
SMILES: C1=CN(C(=O)N=C1)C2C(C(C(O2)CO)O)O
InChi: InChI=1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2/t5-,6-,7-,8-/m1/s1
InChi Key: RPQZTTQVRYEKCR-WCTZXXKLSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |