BW
ZO1 Rabbit monoclonal Antibody | BS9802M
- SKU:
- BW-BS9802M
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- Usually ships in 5 working days
Description
ZO1 Rabbit monoclonal Antibody | BS9802M | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: ICC IHC
Application Range: ICC: 1:200 IHC: 1:200
Background: Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. ZO1 plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of ZO1 and does not cross-react with related proteins.
Molecular Weight: ~ 194 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Tight junction protein ZO-1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1; TJP1; ZO1
Immunogen: This Antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to ZO1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified
Pathway: