26

3907BP | APG7/ATG7 Blocking Peptide DataSheetAntibody Target: APG7/ATG7 Accession #: NP_001012097Gene ID: 312647Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Aphidicolin is a natural tetracyclic diterpene antibiotic which shows antiviral activity against herpes simplex. In eukaryotic cells, it is a cell-permeable, reversible inhibitor of DNA replication,...

A potent, cell permeable inhibitor of histone deacetylase (IC₅₀ = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC₅₀ = 50 – 100 nM) and induces the transcriptional...

A naturally occurring plant flavone that displays remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties. It selectively inhibits casein kinase II (CK2). Apigenin inhibits CK2...

Apilimod is a small molecule that inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c-Rel. It suppresses the...

Apixaban is a potent, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM). Apixaban is an effective anticoagulant in both preclinical and clinical models of venous and...

Apolipoprotein-D (Apo-D) is mainly associated with high density lipoproteins in human plasma. It is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apo-D...

Apoliprotein J (APO-J), also named Clusterin, is a 75-80 kD disulfide-linked heterodimeric protein. The precursor polypeptide chain is cleaved proteolytically to remove the 22-mer secretory signal...

Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 µg/ml in plasma, increases 500-1000...

Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 g/ml in plasma, increases...

ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in...

ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in...

6712 | ApoA1 Antibody (NT) DataSheet

5693 | ApoA1 Antibody DataSheet

6713 | ApoA4 Antibody (NT) DataSheet

6717 | ApoA5 Antibody (NT) DataSheet

K401 | ApoBrdU DNA Fragmentation Assay Kit DataSheet

K404 | ApoBrdU Red DNA Fragmentation Kit DataSheet

K403 | ApoBrdU-IHC DNA Fragmentation Assay Kit DataSheet

6718 | ApoC2 Antibody (Center) DataSheet

6719 | ApoD Antibody (NT) DataSheet

K402 | ApoDIRECT DNA Fragmentation Assay Kit DataSheet

6720 | ApoE Antibody (CT) DataSheet

5760 | ApoE2 Antibody DataSheet

ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to...

5696 | ApoE3 Antibody DataSheet

ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to...

5699 | ApoE4 Antibody DataSheet

ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to...

6721 | ApoER2 (LRP8) Antibody (CT) DataSheet

6722 | ApoF Antibody (Center) DataSheet

6758 | ApoJ/Clusterin Antibody (NT) DataSheet

6668 | ApoJ/Clusterin Antibody DataSheet

Native Apolipoprotein J (ApoJ), also named Clusterin, is a heavily glycosylated, 75-80 kDa disulfide-linked heterodimeric protein. Despite being cloned since 1989, no genuine function has been...

Native Apolipoprotein J (ApoJ), also named Clusterin, is a heavily glycosylated, 75-80 kDa disulfide-linked heterodimeric protein. Despite being cloned since 1989, no genuine function has been...

Apolipoprotein A-II(APO-A2) stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. It is produced by the liver and is involved in...

ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in...

APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of...

Apolipoprotein AIV (Apo AIV) is a glycoprotein synthesized by the human intestine. Synthesis appears to be stimulated by the absorption of high density lipoproteins that are rich in triglycerides...

3661 | ApoLipoprotein B Antibody DataSheet

Apolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90 mg per 100 ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and...

Apolipoprotein CI is one of the protein components of VLDL lipoprotein. The normal plasma concentration of Apo CI is 4-7 mg per 100 ml. Elevated levels of Apo CI may offer some protection from...

Apo CII activates lipoprotein lipase which then hydrolyzes VLDL triglyceride to form IDL (intermediate density lipoproteins). The concentration of Apo CII in normal plasma is 3-8 mg per 100 ml.4704 |...

Apo CIII inhibits the activation of lipoprotein lipase by Apo CII. Reduced levels of Apo CIII result in higher fatty acid uptake from plasma triglycerides into adipose tissue. Thus, Apo CIII is a...

K4696 | Apolipoprotein E human Elisa Kit DataSheet

Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell...

K4699 | Apolipoprotein E4/Pan-ApoE human Elisa Kit DataSheet

Apomorphine is an archetypical dopamine pan-receptor agonist. It displays anti-Parkinson’s activity in vivo. Protects against MPTP-induced neurotoxicity in a mouse model. In clinical use for...

Apoptosis activator 2 is a cell-permeable apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and...

Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction. It does not directly inhibit caspase-3, but effects are attributable to the inhibition of caspase-3 activation.Apoptosis...

K258 | Apoptotic Cell Isolation Kit DataSheet

K170 | Apoptotic DNA Ladder Isolation Kit DataSheet

Apoptozole is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14 μM, respectively. Apoptozole dose-dependently induces apoptosis in cancer cells (IC₅₀ = 5-7 µM). It...

5324 | ApoSAA Antibody DataSheet

K254 | ApoSENSOR ATP Cell Viability Bioluminescence Assay Kit DataSheet

6963 | Apotransferrin Antibody DataSheet

Transferrin less the iron molecule. Like transferrin, apotransferrin has a physiological role in the transportation and distribution of iron among the body organs. It is also an important transport...

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution...

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution...

APP, also known as amyloid beta A4 protein, functions as a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides...

5045 | APP Antibody (CT) DataSheet

Apramycin is an aminoglycoside antibiotic that binds the deep groove of RNA and effectively inhibits ribosomal translocation blocking protein synthesis. Displays bactericidal activity against most...

Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded...

Apremilast is a potent PDE4 (phosphodiesterase 4) inhibitor (IC₅₀ = 74 nM). It reduces TNF-α production in human synovial cells and significantly suppresses experimental arthritis.Apremilast is a...

Aprepitant is an anti-emetic compound that acts as a selective antagonist of human NK1 receptor (Kis = 3 and 454.1 nM for hNK1 and hNK3, respectively; IC₅₀ = 0.09 nM for hNK1). Its prodrug is...

APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family...

APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family...

7007 | Aprotinin Antibody DataSheet

Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung,...

Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung,...

APS-2-79 is a KSR-dependent MAPK modulator.APS-2-79 is a KSR-dependent MAPK modulator.B1696 | APS-2-79 DataSheetAlternate Name/Synonyms: APS-2-79; APS279 (hydrochloride); APS 2 79 (hydrochloride);...

APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC₅₀ = 5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2. Also acts as a...

APY29 is a highly potent and selective allosteric modulator of IRE1α. Under endoplasmic reticulum (ER) stress, unfolded proteins accumulate in the ER to activate the ER transmembrane...

AR-42 is a potent histone deacetylase inhibitor (HDACi). It induces growth inhibition, cell- cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 also promotes hyperacetylation of H3, H4,...

AR-C155858 is a potent Inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2 (Ki values are 2.3 and

AR-7, also known as Atypical retinoid 7, is a potent and selective enhancer of the chaperone-mediated autophagy (CMA). Acts as a chemical activator on RARα activity.AR-7, also known as Atypical...

E4602 | Arachidonic Acid AA Elisa Kit DataSheet

Precursor to a large family of eicosanoids. Activator for several protein kinase C isotypes.Arachidonic acid is a precursor to a large family of eicosanoids. Activator for several protein kinase C...

Arachidonyl-2-chloroethylamide (ACEA) is a high affinity agonist of cannabinoid receptor CB1. It binds to the CB1 receptor with high affinity (Ki value of 1.4 nM) and to the CB2 receptor with low...

Aramchol is a conjugate of cholic acid and arachidic acid. It is a synthetic fatty-acid/bile-acid conjugate (FABAC). It significantly reduces hepatic fat content in a high fat diet animal model. It...

Arcyriaflavin A inhibits cyclin-dependent kinase 4 (CDK4) with an IC₅₀ of 140 nM. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC₅₀ of 25 nM. It inhibits the...

Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC₅₀ = 11.1 μM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline...

A1080 | ARG1 Polyclonal Antibody DataSheet

ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of...

Agatroban is a potent and competitive thrombin inhibitor (Ki = 19 nM) that displays anticoagulant activity. Active in vivo.Agatroban is a potent and competitive thrombin inhibitor (Ki = 19 nM) that...

Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. It is the final enzyme of the urea cycle. At least two isoforms of mammalian arginase exist...

K755 | Arginase Activity Colorimetric Assay Kit DataSheet

K567 | Arginase I ARG1 Inhibitor Screening Kit Colorimetric DataSheet

K384 | Arginine Assay Kit Fluorometric DataSheet

Arginine deiminase (ADI) is a potential anti-tumor biologics for the treatment of arginine-auxotrophic tumors, such as hepatocellular carcinomas and melanomas. ADI hydrolyzes arginine to citrulline...

Argininosuccinate Synthetase is part of the urea cycle. It catalyzes aspartate, citrulline, and ATP to form argininosuccinate. Mutations in the enzyme cause Citrullinemia, preventing the liver from...

Arglabin is a potent anti-inflammatory and anticancer agent. It also acts as a Farnesyltransferase inhibitor and antiatherogenic compound. Prevents the accumulation of lipid containing plaques in...

Aripiprazole is a high affinity dopamine D2 and 5-HT1A receptor partial agonist (Ki values are ~1.64 and 5.59 nM respectively). Also 5-HT2A antagonist (Ki = 8.7 nM). Aripiprazole is a clinically...

ARN-272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC₅₀ = 1.8 µM). It attenuates anandamide internalization and deactivation in vitro and in vivo respectively. Displays analgesic effects...

ARN-509 is a selective and competitive androgen receptor (AR) inhibitor (IC₅₀ = 16 nM). ARN-509 selectively binds the androgen receptor and impairs its nuclear translocation and DNA binding to...

3599 | Aromatase Antibody DataSheet

3599BP | Aromatase Blocking Peptide DataSheetAntibody Target: Aromatase Accession #: P11511 Gene ID: 1588Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

K983 | Aromatase CYP19A Activity Assay Kit Fluorometric DataSheet

K984 | Aromatase CYP19A Inhibitor Screening Kit Fluorometric DataSheet

ARQ-531 is a potent, reversible non-covalent Bruton’s Tyrosine Kinase (BTK) inhibitor, with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.ARQ-531 is a potent, reversible...