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Cantharidin is a natural toxin produced by blister beetles that moderately inhibits protein phosphatases 1 (PP1) (IC₅₀ = 1.7 μM) and PP2A (IC₅₀ = 0.2 μM) and only weakly inhibits the activity of PP2B...

A pre-prodrug of 5-fluorouracil (5-FU). After oral uptake, capecitabine is first metabolized to 5'-deoxy-5-fluorocytidine (5'-DFCR), which occurs mainly in the liver by carboxyl-esterase. The...

Caper Antibody | 3733

Capmatinib is an ATP competitive inhibitor of c-MET kinase or hepatocyte growth factor receptor (HGFR). Binding of Hepatocyt Growth Factor to c-MET receptor causes activation of multiple downstream...

Capsaicin is the ingredient found in different types of hot peppers, such as cayenne peppers, that makes the peppers spicy hot. Prototype vanilloid receptor agonist (pEC₅₀ values are 7.97 and 7.10 at...

Captopril is an angiotensin-converting enzyme (ACE) inhibitor (IC₅₀ = 0.022 μM). Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and...

Carbamazepine is an inhibitor of neuronal voltage-gated Na+ channels. It displays anticonvulsant activity and potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor...

Carbenicillin disodium is a member of the carboxypenicillin β-lactam antibiotic family. Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial...

Carbonic anhydrase 3 (CA3) is also known as Carbonate dehydratase III, Carbonic anhydrase III, which belongs to the alpha-carbonic anhydrase family. These carbonic anhydrases are a class of...

E4353 | Carbonic anhydrase 9 CA9 Human Elisa Kit DataSheet

K472 | Carbonic Anhydrase CA Activity Assay Kit Colorimetric DataSheet

K473 | Carbonic Anhydrase CA Inhibitor Screening Kit Colorimetric DataSheet

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including...

Carbonic anhydrase (CA) is an enzyme that catalyses rapid conversion of carbon dioxide to bicarbonate and protons (CO2 + H2O HCO3 + H+). Most carbonic anhydrases contain a zinc ion in their active...

CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, this protein lacks carbonic anhydrase activity (i.e., the reversible...

Carbonyl Cyanide m-Chlorophenylhydrazone is a protonophore (H⁺ ionophore) and an uncoupler of oxidative phosphorylation in mitochondria. Displays several effects on cellular calcium.Carbonyl Cyanide...

An analog of Cisplatin with reduced nephrotoxicity. Displays potent anti-tumor activity.Carboplatin is an analog of Cisplatin with reduced nephrotoxicity. Displays potent anti-tumor activity.1553 |...

Carboxyatractyloside is a plant-derived natural heteroglucoside that prevents mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di- and...

Ces1d, also known as carboxylesterase 1D, is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds. It is the principle lipase of white...

E4634 | Carboxymethyl Lysine CML Elisa Kit DataSheet

3825BP | Carboxypeptidase A1 (CPA1) Blocking Peptide DataSheetAntibody Target: Carboxypeptidase A1 (CPA1) Accession #: P15085Gene ID: 1357Appearance: Colorless liquidConcentration: 0.5...

3825 | Carboxypeptidase A1 (CPA1) Antibody DataSheet

3816BP | Carboxypeptidase A2 (CPA2) Blocking Peptide DataSheetAntibody Target: Carboxypeptidase A2 (CPA2) Accession #: Q504N0Gene ID: 232680Appearance: Colorless liquidConcentration: 0.5...

3816 | Carboxypeptidase A2 (CPA2) Antibody DataSheet

CPA4, also known as carboxypeptidase A4, is a secreted, zinc-dependent metallocarboxypeptidase that removes the C-terminal amino acid from peptides having a free C-terminal carboxyl group. CPA4 is...

Carboxypeptidase B (EC 3.4.17.2) catalyzes hydrolysis of the basic amino acids lysine, arginine and ornithine from the C-terminal end of polypeptides. Carboxypeptidase B is inhibited by arginine,...

Cell-permeable. A potent inhibitor of MET, vascular endothelial growth factor receptor 2 (VEGFR2), and RET, with robust antiangiogenic, antitumor, and anti-invasive effects.Carbozantinib is a potent...

Carcinoembryonic Antigen CEA human Elisa Kit | K4805

Cadazolid is a novel oxazolidinone antibiotic effective against multi-resistant, gram-positive bacteria. Cadazolid displays potent in vitro activity against Clostridium difficile, including the...

Cell-permeable. Induces differentiation of mouse embryonic stem cells (ESCs) into cardiomyocytes (EC₅₀ = 100 nM).Cardiogenol C hydrochloride induces differentiation of mouse embryonic stem cells...

K944 | Cardiolipin Assay Kit Fluorometric DataSheet

E4659 | Cardiolipin IgA Elisa Kit DataSheet

E4660 | Cardiolipin IgG Elisa Kit DataSheet

E4658 | Cardiolipin IgG, IgA, IgM Elisa Kit DataSheet

E4661 | Cardiolipin IgM Elisa Kit DataSheet

Cardiolipin probe is an excellent fluorescent probe for the detection and quantification of cardiolipin (CL). It displays improved sensitivity and excellent selectivity for CL over other major...

Human Cardiotrophin-1 (CT-1) is a member of the leukemia inhibitory/ciliary neurotrophic factor/Oncostatin M/interleukin-6/interleukin-11 family of cytokines. Cardiotrophin-1 affects cells through...

CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various...

Carfilzomib (PR-171) is a next generation, irreversible and selective inhibitor of the chymotrypsin-like activity of the proteasome. It displays potent antineoplastic activity.Carfilzomib (PR-171) is...

Carglumic acid is an activator of carbamoyl phosphate synthetase 1 (CPS1), the first enzyme in the urea cycle that is responsible for removal and detoxification of ammonia, making this drug a...

3734R | CARM1 Antibody DataSheet

3734RBP | CARM1 Blocking Peptide DataSheetAntibody Target: CARM1 Accession #: EDL25201Gene ID: 59035Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3734 | CARM1 Polyclonal Antibody DataSheet

Carmofur is derivative of 5-flurouracil (Cat. No. B1519) that acts as an inhibitor of acid ceramidase (IC₅₀ = 79 nM for the rat enzyme). It reduces acid ceramidase activity in a dose- and...

Carmustine is a nitrogen mustard and a cell-cycle phase nonspecific alkylating antineoplastic agent. It forms interstrand crosslinks in DNA, which prevents DNA replication and transcription leading...

Carnosic acid is a diterpene compound exhibiting antioxidative, anticancer, anti-angiogenic, anti-inflammatory, anti-metabolic disorder, and hepatoprotective and neuroprotective activities. It...

K809 | Carrez Clarification Reagent Kit DataSheet

Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA...

A1069 | Cas9 Monoclonal Antibody DataSheet

6687 | Caspase 1 Antibody DataSheet

K132 | Caspase Colorimetric Substrate Set DataSheet

K134 | Caspase Colorimetric Substrate Set II DataSheet

K138 | Caspase Colorimetric Substrate Set II Plus DataSheet

K136 | Caspase Colorimetric Substrate Set Plus DataSheet

A convenient set containing seven ready-to-use capase family inhibitors. The set contains 25 µl (2 mM in DMSO) each of the following five inhibitors: Caspase-1 Inhibitor, Z-YVAD(OMe)-FMK; Caspase-2...

A convenient set containing eight ready-to-use capase family inhibitors. The set contains 25 µl (2 mM in DMSO) each of the following five inhibitors: Caspase-1 Inhibitor, Z-YVAD(OMe)-FMK; Caspase-2...

A convenient set containing twelve ready-to-use capase family inhibitors. The set contains 25 µl (2 mM in DMSO) each of the following five inhibitors: Caspase-1 Inhibitor, Z-YVAD(OMe)-FMK; Caspase-2...

A convenient set containing five ready-to-use capase family inhibitors. The set contains 25 µl (2 mM in DMSO) each of the following five inhibitors: Caspase-1 Inhibitor, Z-YVAD(OMe)-FMK; Caspase-3...

K131 | Caspase Fluorometric Substrate Set DataSheet

K133 | Caspase Fluorometric Substrate Set II DataSheet

K137 | Caspase Fluorometric Substrate Set II Plus DataSheet

K135 | Caspase Fluorometric Substrate Set Plus DataSheet

A synthetic peptide that irreversibly inhibits ICE-family protease/caspase activity and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the...

3019 | Caspase-1 Antibody DataSheet

3019BP | Caspase-1 Blocking Peptide DataSheetAntibody Target: Caspase-1 Accession #: NP_150636Gene ID: 834Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: In phosphate buffered saline...

E4588 | Caspase-1 CASP1 Human Elisa Kit DataSheet

E4594 | Caspase-1 CASP1 Rat Elisa Kit DataSheet

K111 | Caspase-1 Colorimetric Assay Kit DataSheet

K110 | Caspase-1 Fluorometric Assay Kit DataSheet

A synthetic peptide that irreversibly inhibits ICE (interleukin-1β converting enzyme, Ki = 0.76 nM) activity. YVAD is the preferred recognition sequence for ICE/caspase-1. The inhibitor is designed...

K4180 | Caspase-1 Mouse Elisa Kit DataSheet

Ready-to-use fluorometric substrate for caspase-1/ICE and related caspases that recognize the amino acid sequence YVAD. Caspase-1 and related caspase activity can be quantified by fluorescent...

Ready-to-use colorimetric substrate for caspase-1/ICE and related caspases that recognize the amino acid sequence YVAD. Caspase-1 and related caspase activity can be quantified by spectrophotometric...

Caspase-1 (also know as ICE) is a prototypical member of the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa proenzyme. The pro-enzyme is matured by proteolysis...

Caspase-1 (also know as ICE) is a prototypical member of the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa proenzyme. The pro-enzyme is matured by proteolysis...

Caspase-10 Antibody | 3410

3410BP | Caspase-10 Blocking Peptide DataSheetAntibody Target: Caspase-10 Accession #: AAD28403Gene ID: 843Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

K125 | Caspase-10 Colorimetric Assay Kit DataSheet

K124 | Caspase-10 Fluorometric Assay Kit DataSheet

A synthetic peptide inhibitor that inhibits caspase-10 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor...

Ready-to-use fluorometric substrate for AEVD-dependent caspases. Activity of AEVD-dependent caspase activity can be quantified by fluorescent detection of free AFC after cleavage from the peptide...

Ready-to-use colorimetric substrate for caspases that recognize the amino acid sequence AEVD. Caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleaved...

Caspase-10/a (also known as Mch4) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-10 also exists in cells as an inactive proenzyme. During apoptosis...

Caspase-10b (also known as FLICE 2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-10 also exists in cells as an inactive proenzyme. During apoptosis...

3021 | Caspase-11 Antibody DataSheet

3021BP | Caspase-11 Blocking Peptide DataSheetAntibody Target: Caspase-11 Accession #: NM_007609Gene ID: 12363Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

3282 | Caspase-12 Antibody DataSheet

3282BP | Caspase-12 Blocking Peptide DataSheetAntibody Target: Caspase-12 Accession #: NM_009808Gene ID: 12364Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

K139 | Caspase-12 Fluorometric Assay Kit DataSheet

A synthetic peptide that irreversibly inhibits caspase-12 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is...

Ready-to-use fluorometric substrate for caspases that recognize the amino acid sequence ATAD. Caspase activity can be quantified by fluorescent detection of free AFC after cleaved from the peptide...

A synthetic peptide inhibitor that inhibits caspase-13 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor...

Ready-to-use fluorometric substrate for caspase-13 and related caspases that recognize the amino acid sequence LEED. Caspase-13 and related caspase activity can be quantified by fluorescent detection...

3011 | Caspase-14 Antibody DataSheet

3011BP | Caspase-14 Blocking Peptide DataSheetAntibody Target: Caspase-14Accession #: P31944Gene ID: 23581Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3027 | Caspase-2 Antibody DataSheet

3027BP | Caspase-2 Blocking Peptide DataSheetAntibody Target: Caspase-2 Accession #: D28492Gene ID: 12366Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

E4589 | Caspase-2 CASP2 Human Elisa Kit DataSheet

E4590 | Caspase-2 CASP2 Rat Elisa Kit DataSheet

K117 | Caspase-2 Colorimetric Assay Kit DataSheet