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6859 | Chd1 polyclonal antibody DataSheet

Cell-permeable. A selective protein kinase C (PKC) inhibitor (IC₅₀ =0.66 µM). Chelerythrine is at least 100-fold more selective for PKCs than for other kinases. It induces apoptotic cell death in...

Chemerin is a chemoattractant expressed in white adipose, liver and lung tissues. Chemerin is a ligand for the G-protein coupled receptor known as ChemR23 (or chemokine-like receptor-1), which is...

offers low price and high quality Pre-designed Chemically Modified siRNA Oligo Set for the customers who intend to ensure the inhibition efficiency in siRNA experiments. The customer needs to...

offers low price and high quality Pre-designed Chemically Modified siRNA Oligo Set for the customers who intend to ensure the inhibition efficiency in siRNA experiments. The customer needs to...

offers low price and high quality Chemically Modified siRNA Oligos. All our siRNA oligos undergo vigorous process monitoring and strict quality control. Length and labeling are systematically...

Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism. EC50 concentrations for activation of FXR (farnesoid X receptor)...

A natural metabolite produced by genus Chaetomium. Acts as an inhibitor of HIF-1 formation by disrupting the binding of p300 to both HIF-1α and HIF-2α. Histone H3K9 methyltransferases G9a and Suv39h...

6648 | Chicken Growth Hormone Antibody DataSheet

Cell-permeable. A new benzamide class of histone deacetylase (HDAC) inhibitor with marked anti-tumor activity. It increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at...

CHIP is the C-terminus of HSC70 Interacting Protein4898 | CHIP human recombinant DataSheetBiomolecule/Target: N/ASynonyms: CHIP, UBOX1, HSPABP2, NY-CO-7, SDCCAG7, STUB1, STIP1 homology and U...

CHIR99021 trihydrochloride is the hydrochloride salt of the potent and highly selective glycogen synthase kinase-3β (GSK-3β) inhibitor CHIR99021 (Cat. No. 1677).CHIR99021 trihydrochloride is the...

A potent and highly selective inhibitor of glycogen synthase kinase-3β (GSK-3β) (IC₅₀ = 6.7 nM). CHIR99021 has been shown to allow for long-term expansion of murine embryonic stem cells in a...

CHIR-090 is a potent, low, tight-binding inhibitor of LpxC (UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase) (Ki = 4.0 nM). Antibacterial agentCHIR-090 is a potent, low,...

CHIR-124 is a quinolone-based inhibitor of Checkpoint kinase-1 (Chk1). It potently and selectively inhibits Chk1 in vitro with an IC₅₀ of 0.3 nM. It interacts synergistically with topoisomerase...

Cell-permeable. CHIR-98014 is a potent, selective and ATP-competitive inhibitor of GSK3α and GSK3β (IC₅₀ = 0.65 and 0.58 nM, respectively). In addition, CHIR-98014 displays 500 to greater than...

K512 | Chitotriosidase Activity Assay Kit Fluorometric DataSheet

CHK1 is a 56 kd serine/threonine protein kinase that was originally identified in fission yeast to play a role in activation of the DNA damage checkpoint in the G2 phase of the cell cycle (1). CHK1...

3305 | Chk2 Antibody DataSheet

A cell-permeable, potent, and ATP-competitive inhibitor of Chk2 (checkpoint kinase 2; IC₅₀ = 15 nM; Ki = 37 nM). Displays ~1,000-fold greater selectivity for Chk2 compared to Cdk1/cyclin B and CK1...

Chk2 is the mammalian homolog of the Saccharomyces cerevisiae Rad53 and Schizosaccharomyces pombe Cds1 protein kinases required for the DNA damage and replication checkpoints. Chk2 is rapidly...

K4230 | Chloramphenicol CAP Elisa Kit DataSheet

Chloramphenicol is a bacteriostatic antibiotic that inhibits bacterial protein synthesis. Displays a broad spectrum antibiotic activity targeting a wide variety of gram positive and gram negative...

K530 | Chloride Colorimetric Assay Kit DataSheet

An antimalarial drug. Inhibits autophagy of glioma cells via a mechanism distinct from that of 3-Methyladenine.Chloroquine Diphosphate is an antimalarial drug. Inhibits autophagy of glioma cells via...

Chlorpromazine is a dopamine receptor antagonist; reduces neurotransmitter binding. Inhibits nitric oxide synthesis in mouse brain cytosol. Also acts as an antagonist of nAChR, histamine and 5-HT...

Chlorpropamide belongs to the sulfonylurea class of insulin secretagogues, is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It acts by...

Chlorprothixene is a thioxanthine antipsychotic drug. It is an antagonist of dopamine and histamine receptors with Ki values of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and...

E4537 | CHO Host Cell Proteins Elisa kit DataSheet

K587 | Cholesterol Detection Kit cell-based DataSheet

K582 | Cholesterol Efflux Fluorometric Assay Kit cell-based DataSheet

Cholesteryl hemisuccinate is a useful cholesterol-based detergent that increases the stability of G protein-coupled receptors (GPCRs). Together with mutagenesis studies and recent GPCR structures, it...

Choline Kinase (E.C. 2.7.1.32) is an enzyme which catalyzes the first reaction in the choline pathway for the synthesis of the membrane phospholipid phosphatidylcholine. It belongs to the family of...

K476 | Choline Kinase ChoK Activity Assay Kit Fluorometric DataSheet

K615 | Choline/Acetylcholine Quantification Colorimetric/Fluorometric Kit DataSheet

K975 | Cholinesterase Activity Assay Kit Colorimetric DataSheet

’s hCG is biologically active compared to standard. The biological activity of hCG is determined by using the seminal vesicle weight gain test in male rats described in the "Chorionic Gonadotrophins"...

5778 | Chorionic Gonadotropin (CG) Antibody DataSheet

K7424 | Chorionic Gonadotropin hCG human Elisa Kit DataSheet

CHR2797 is a novel metalloenzyme inhibitor. It inhibits proliferation, and induces growth arrest and apoptosis in myeloma cells, including cells resistant to conventional chemotherapeutics.CHR2797 is...

K4241 | Chromogranin A CgA Elisa Kit DataSheet

Chrysin is a natural flavonoid that displays antioxidant, anti-inflammatory, and anticancer properties. It inhibits aromatase and also suppresses human immunodeficiency virus (HIV) activation in...

Chrysophenol is a natural anthraquinone derivative that displays antibacterial, antiviral, anti-inflammatory, and anticancer activities in various research models. Chrysophanol has been shown to...

A pyridyl cyanoguanidine derivative that displays potent antitumor activity. Also acts as an inhibitor of Nampt/visfatin, NF-kB and IkB kinase. In addition, CHS-828 induces programmed cell death and...

Chylomicrons are the large triglyceride-rich lipoproteins of enteric origin that carry exogenous triglycerides into the plasma. Circulation of chylomicrons distributes dietary triglyceride to adipose...

K352 | Chymotrypsin Activity Assay Kit Fluorometric DataSheet

Chymotrypsin is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide...

Chymotrypsinogen-B1 (CTRB1) belongs to the serine protease family of enzymes and forms a main precursor of the pancreatic proteolytic enzymes. CTRB1 is located next to a related chymotrypsinogen gene...

CHZ868 is a potent and selective type II JAK2 inhibitor (IC₅₀ = 110 nM). JAK2 and MPL mutant cell lines are sensitive to CHZ868, including type I JAK inhibitor persistent cells. CHZ868 displays...

Cell-permeable. A histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100 µM for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro...

3180A | cIAP-1 Antibody DataSheet

3180ABP | cIAP-1 Blocking Peptide DataSheetAntibody Target: cIAP-1 Accession #: Q13490Gene ID: 329Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3180BP | cIAP-1 Blocking Peptide DataSheetAntibody Target: cIAP-1 Accession #: Q13490Gene ID: 329Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3180 | Anti-cIAP-1 (HIAP-2) Polyclonal Antibody DataSheet

3181BP | cIAP-2 Blocking Peptide DataSheetAntibody Target: cIAP-2 Accession #: NP_892007Gene ID: 330Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3181 | cIAP-2/HIAP-1 Antibody DataSheet

Ciclopirox olamine (CPX) is an antifungal agent that has recently demonstrated promising anti-neoplastic activity against hematologic and solid tumors. Also inhibits ferroptosis.Ciclopirox olamine...

Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations,...

Cell-permeable. A potent, competitive, and reversible antagonist of the orphan receptor GPR35 (Ki = 12.8 nM). Prevents the GPR35-mediated increase in ERK1/2 phosphorylation and β-arrestin recruitment...

CID-1067700 is a potent, and competitive, Ras-related GTPase inhibitor. It binds the nucleotide binding pocket of Rab7 with a Ki value of 13 nM, preventing BODIPY-linked GTP and GDP binding with EC₅₀...

Cell-permeable. CID-2011756 is an ATP-competitive protein kinase D (PKD) inhibitor with IC₅₀ values of 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively. Inhibits phorbol ester-induced...

CID-5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor). disrupted BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove. This compound...

CID-5951923 is an Inhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC₅₀ = 2.3 μM). Significantly reduces endogenous KLF5 protein levels and decreases viability of colon cancer cells,...

CID-755673 is a selective small molecule inhibitor of protein kinase D (PKD) (IC₅₀s = 182, 280, 227 nM for PKD1, 2, and 3, respectively). It exhibits higher selectivity for PKD over Akt, polo-like...

6968 | CIDE-C Antibody DataSheet

Cidofovir is a selective inhibitor of viral DNA synthesis through the selective inhibition of viral DNA polymerase. In vitro, cidofovir is converted to cidofovir diphosphate which incorporates into...

An antidiabetic drug. A thiazolidinedione (TDZ) type of antihyperglycemic agent. It displays antihyperglycemic activity in genetically obese C57 Bl/6 ob/ob mice and is a selective PPARɣ agonist (EC₅₀...

3314 | CIKS/Act1 Antibody DataSheet

CIL56 is a small molecule that acts as a selective ferroptosis inducer through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated,...

Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase. It inhibits human renal dipeptidase (Ki = 0.7 μM), porcine dipeptidase (IC50 = 0.11 μM), and bacterial...

Cilazapril is a pyridazine angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. It is a prodrug that is hydrolyzed after...

Cilengitide is a cyclo-(Arg-Gly-Asp-D-Phe-Val) (cRGDfV) peptide that acts as an integrin αVβ3 receptor antagonist. It inhibits adhesion and induces apoptosis of U87MG and U373MG malignant glioma (MG)...

Cilofexor (GS-9674), is a nonsteroidal bile acid farnesoid X receptor (FXR) agonist. It improves markers of cholestasis and liver injury in patients with PSC. PSC is an incurable rare chronic liver...

Cilomilast is an orally active, second-generation phosphodiesterase (PDE) inhibitor that may be effective in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It has high...

A selective type III phosphodiesterase-3 (PDE3) inhibitor. Displays limited selectivity for PDE3A versus PDE3B (IC₅₀ = 27 and 50 nM). This inhibitory effect increases intracellular cAMP and inhibits...

Cilostazol is a clinically approved phosphodiesterase III (PDE3) inhibitor (IC₅₀ = 0.2 µM) and anti-thrombotic agent. It inhibits platelet aggregation and is a direct arterial vasodilator.Cilostazol...

Cimetidine is a potent histamine H2 receptor antagonist (Ki = 0.6 μM). It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1...

Cimicoxib is an imidazole derivative and a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and specific cyclooxygenase-2 (COX-2) inhibitor. Used in veterinary medicine to treat...

Cinacalcet is a calcimimetic and an allosteric agonist of the calcium-sensing receptor. Cinacalcet increases the sensitivity of calcium-sensing receptors on chief cells in the parathyroid gland to...

CINK4 is a triaminopyrimidine derivative that inhibits Cdk4/cyclin D1 and Cdk6/cyclin D1 activity with IC₅₀ values of 1.5 and 5.6 μM, respectively. It reduces retinoblastoma protein phosphorylation...

E4365 | Ciprofloxacin Cipro Elisa Kit DataSheet

CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. Increases channel opening efficiency and enhances NMDA receptor responses.CIQ is a subunit-selective...

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a...

A platinum coordination complex with potent anti-neoplastic activity.Cisplatin is a platinum coordination complex with potent anti-neoplastic activity.1550 | Cisplatin DataSheetAlternate...

Citarinostat (ACY-241), is a potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor with IC₅₀ values of 4 nM and 76 nM for HDAC6 and HDAC3, respectively. Displays...

5286 | CITED2 Antibody (NT) DataSheet

K655 | Citrate Colorimetric/Fluorometric Assay Kit DataSheet

K318 | Citrate Synthase Activity Colorimetric Assay Kit DataSheet

CK2 inhibitor is a 3-carboxy-4(1H)-quinolone which selectively inhibits casein kinase 2 (CK2) with an IC₅₀ value of 0.3 μM. It competitively inhibits binding of ATP with a Ki value of 0.06 µM.CK2...

CK2 inhibitor selectively inhibits casein kinase 2 (CK2) with an IC₅₀ of 0.125 μM. CK2 is a potential protein kinase target for the development of antitumor, antiviral and anti-inflammatory drugs.CK2...

CK2 (also termed casein kinase II ) is a serine-threonine protein kinase whose targets include many critical regulators of cellular growth. It is highly expressed in a lympho pro-liferative disease...

CL-387785 is an irreversible inhibitor of EGF-stimulated autophosphorylation of tyrosine residues in the epidermal growth factor receptor (EGFR) in vivo (IC₅₀ = 250-490 pM) and blocks EGF-mediated...

Cl-Amidine (hydrochloride) is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor. It catalyzes the post-translational modification of arginine residues on histones to form citrulline. The...

Cladribine is an adenosine deaminase inhibitor. It is phosphorylated by deoxycytidine kinase, resulting in its intracellular accumulation and inhibition of ribonucleotide reductase. Cladribine...

Clarithromycin is a semisynthetic macrolide antibiotic derived from erythromycin. It inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl...

3770 | Claspin Antibody DataSheet

Classic CRISPR sgRNA Synthesis Kit | K1252

Cell-permeable. A highly specific, potent and irreversible proteasome inhibitor. Lactacystin (Cat. No. 1709-200) acts as a precursor for clasto-lactacystin β-lactone and the latter compound is at...

A1004 | Cleaved-Caspase-1 Antibody DataSheet

Clemastine fumarate is a selective histamine H1 receptor antagonist (Ki = 0.26 nM); also displays high affinity for muscarinic receptors (Ki = 16 nM). Also acts as a positive allosteric modulator of...