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A 10 mM (5 mg in 1.55 ml) of the JAK1 inhibitor PF-04965842 (Cat. No. B2470) in anhydrous DMSOA 10 mM (5 mg in 1.55 ml) of the JAK1 inhibitor PF-04965842 (Cat. No. B2470) in anhydrous DMSOB2622 |...

A 5 mM (2 mg in 1.15 ml), sterile-filtered solution of the BET bromodomain inhibitor PFI-1 (Cat. No. 2203) in anhydrous DMSO.EZSolution™ PFI-1 is a 5 mM (2 mg in 1.15 ml), sterile-filtered solution...

A solution (20 mg/ml) of the antibiotic Phleomycin (Cat. No. 2724) in deionized water. Sterile-filtered.A solution (20 mg/ml) of the antibiotic Phleomycin (Cat. No. 2724) in deionized water...

A 10 mM (5 mg in 1403 µl) of PPARγ agonist Pioglitazone (Cat. No. 1877) in anhydrous DMSO.Pioglitazone is a thiazolidinedione (TZD) derivative that acts as a selective peroxisome...

EZSolution™ Propidium Iodide | B3348Description: Propidium iodide (PI) is a nuclear and chromosome counterstain commonly used to detect dead cells in a population. PI binds to double-stranded DNA,...

’s EZSolution™ Protein Stabilizer is a very effective BSA alternative. It consists of a proprietary protein expressed in E. coli. The proprietary formulation helps protect proteins and enzymes...

A serine protease that displays the ability to digest native proteins, thereby inactivating enzymes such as DNase and RNase without recourse to a denaturation process. It is useful for a variety of...

A 10 mM (1 mg in 260 µl) solution of the proteasome inhibitor PS-341 (Cat. No. 1846) in anhydrous DMSO.EZSolution™ PS-341 is a 10 mM (1 mg in 260 µl) solution of the proteasome inhibitor PS-341 (Cat...

A 10 mM (5 mg in 1744 µl) of the PDK1 activator PS48 (Cat. No. 1869) in anhydrous DMSO.PS48 is an allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds...

A 10 mM (5.0 mg in 960 μl), sterile-filtered solution of the Smoothened (Smo) Receptor Agonist Purmorphamine (Cat. No. 1672) in anhydrous DMSO.EZSolution™ Purmorphamine is a 10 mM (5.0 mg in 960 μl),...

A solution (10 mg/ml, 0.2 µM sterile filtered) of Puromycin Dihydrochloride (Cat. No.1860-100) in deionized water. Suitable for cell culture applications.EZSolution™ Puromycin Dihydrochloride is a...

A 10 mM ( 1 mg in 221 µl) of Pyrintegrin (Cat. No. 1729-1) in anhydrous DMSO.EZSolution™ Pyrintegrin is a 10 mM ( 1 mg in 221 µl) of Pyrintegrin (Cat. No. 1729-1) in anhydrous DMSO.1737 | EZSolution™...

A 10 mM (1 mg in 125 μl) solution of caspase-3 inhibitor Q-DEVD-OPh (Cat. No. 1175-1) in DMSO.EZSolution™ Q-DEVD-Oph is a 10 mM (1 mg in 125 μl) solution of caspase-3 inhibitor Q-DEVD-OPh (Cat. No...

A 10 mM (1 mg in 195 µl) solution of caspase inhibitor Q-VD-OPh (Cat. No, 1170-1) in DMSO.EZSolution™ Q-VD-Oph is a 10 mM (1 mg in 195 µl) solution of caspase inhibitor Q-VD-OPh (Cat. No, 1170-1) in...

A 10 mM (1 mg in 190 µl) solution of the negative control Q-VE-OPh (Cat. No, 1171-1) for the caspase inhibitor Q-VD-OPh (Cat. No. 1170-1) in DMSO.EZSolution™ Q-VD-OPh, Negative Control is a 10 mM (1...

A 5 mM (5 mg in 1093 µl) solution of Rapamycin (Cat. No. 1568-5) in DMSO.EZSolution™ Rapamycin is a 5 mM (5 mg in 1093 µl) solution of Rapamycin (Cat. No. 1568-5) in DMSO.1746 | EZSolution™ Rapamycin...

A 10 mM (5 mg in 1294 µl) of the rapid apoptosis inducer Raptinal (Cat. No. 9626) in anhydrous DMSO.Raptinal is a rapid inducer of apoptosis. Consistent with apoptotic morphological changes, U-937...

A 10 mM (5 mg in 1740 µl) of the ALK5 inhibitor RepSox (Cat. No. 1894) in anhydrous DMSO.RepSox is a TGF-β type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC₅₀ = 4 nM). Can...

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the DNA methyltransferase (DNMT) inhibitor RG-108 (Cat. No. 1679) in anhydrous DMSO.EZSolution™ RG-108 is a 10 mM (5.0 mg in 1.50 ml),...

A 10 mM (1 mg in 162 μl) solution of the p53-MDM2 interaction inhibitor RG7388 (Cat. No. 2577) in anhydrous DMSO.RG7388 is highly a potent and selective inhibitor of p53-MDM2 interaction. RG7388...

RNase A is an endoribonuclease that specifically cleaves the single strand RNA at the phosphodiester bond between the 5’-ribose of a nucleotide and the 3’ OH phosphate group of an adjacent pyrimidine...

A 10 mM (5 mg in 1.82 ml), sterile-filtered solution of the phosphodiesterase-4 (PDE4) inhibitor Rolipram (Cat. No. 2010) in anhydrous DMSO.EZSolution™ Rolipram is a 10 mM (5 mg in 1.82 ml),...

A 10 mM (5 mg in 1038 µl) of the HMG-CoA inhibitor Rosuvastatin (Cat. No. 1955) in anhydrous DMSO.Rosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol...

A 10 mM (5.0 mg in 954 μl), sterile-filtered solution of the HDR (homology-directed repair) enhancer RS-1 (Cat. No. B1118) in anhydrous DMSO.RS-1 (RAD51-stimulatory compound 1) is a high affinity...

A 10 mM (5 mg in 1.63 ml) solution of the potent JAK inhibitor Ruxolitinib (Cat. No. 2139) in anhydrous DMSO.Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with IC₅₀'s of 2.7 and...

A 5 mM (2.45 mg in 1 ml), sterile-filtered solution of the Smo agonist SAG (Cat. No. 1939) in anhydrous DMSO.EZSolution™ SAG is a 5 mM (2.45 mg in 1 ml), sterile-filtered solution of the Smo agonist...

A 10 mM (5 mg in 922 µl) solution of the dual inhibitor of the tyrosine kinases c-Src and Abl Saracatinib (AZD-0530) (Cat. No. 1582) in anhydrous DMSO.A 10 mM (5 mg in 922 µl) solution of the dual...

A 10 mM (1 mg in 265 µl) solution of SB 203580 (Cat. No. 1712-1) in anhydrous DMSO.EZSolution™ SB 203580 is a 10 mM (1 mg in 265 µl) solution of SB 203580 (Cat. No. 1712-1) in anhydrous DMSO.1786 |...

A 10 mM (1 mg in 260 µl) solution of SB-431542 (Cat. No. 1674-1) in anhydrous DMSO.EZSolution™ SB-431542 is a 10 mM (1 mg in 260 µl) solution of SB-431542 (Cat. No. 1674-1) in anhydrous DMSO.1872 |...

A 5 mM (1.92 mg in 1 ml), sterile-filtered solution of the ALK5 inhibitor SB-431542 (Cat. No. 1674) in anhydrous DMSO.EZSolution™ SB-431542, Sterile-Filtered is a 5 mM (1.92 mg in 1 ml),...

A 10 mM (5 mg in 1456 µl) of the ALK5 inhibitor SB-525334 (Cat. No. 2880) in anhydrous DMSO.SB-525334 is a potent and selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI)...

Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1,

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer SCR7 Pyrazine (Cat. No. B1119) in anhydrous DMSO.SCR7 pyrazine is a potent inhibitor of...

A 10 mM (5 mg in 2270 µl) of the JNK inhibitor SP600125 (Cat. No.1669) in anhydrous DMSO.U0126 is a potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2...

Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the...

A 10 mM (5 mg in 2.37 ml), sterile-filtered solution of the STAT3 activation inhibitor Stattic (Cat. No. 2625) in anhydrous DMSO.EZSolution™ Stattic is a 10 mM (5 mg in 2.37 ml), sterile-filtered...

A 1 mM (100 µg/214 µl) solution of Staurosporine (Cat. No. 1048-01) in DMSO.EZSolution™ Staurosporine is a 1 mM (100 µg/214 µl) solution of Staurosporine (Cat. No. 1048-01) in DMSO.1745 | EZSolution™...

A 10 mM (1 mg in 233 µl) of the stem cell fate modulator StemRegenin 1 (Cat. No. 2642) in anhydrous DMSOStemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl...

A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 1645) in anhydrous DMSO.EZSolution™ SU-5402 is a 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 1645) in anhydrous DMSO.2017 | EZSolution™...

A 10 mM (5 mg in 2098 µl) of the VEGFR kinase inhibitor SU-5416 (Cat. No. 9491) in anhydrous DMSO.SU-5416 is a potent tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial...

A 100 mM (25 mg in 469.4 µl) solution of Sunitinib Malate (Cat. No. 1611-25) in anhydrous DMSO.EZSolution™ Sunitinib Malate is a 100 mM (25 mg in 469.4 µl) solution of Sunitinib Malate (Cat. No...

SYBR Green I is a highly sensitive fluorescent DNA binding stain for staining of double stranded DNA (dsDNA) or oligonucleotides in agarose or polyacrylamide gels.SYBR Green I is a highly sensitive...

A 10 mM (5 mg in 888 µl) of the potent inhibitor of FLT kinase, PDGFRβ and c-Kit Tandutinib (Cat. No. 2024) in anhydrous DMSO.A 10 mM (5 mg in 888 µl) of the potent inhibitor of FLT kinase, PDGFRβ...

Inhibitor of TNF-α processing (IC₅₀ = 100 nM), similar to TAPI-0 (Cat. No. 2067-1), but more stable in tissue culture and in vivo. Inhibits TACE and other metalloproteases. Blocks release of TNF- α...

A 100 mM (25 mg in 1007 µl) sterile-filtered solution of Tetrahydrouridine (Cat. No.1671) in H₂O.Tetrahydrouridine is a competitive cytidine deaminase inhibitor and multidrug resistance modulator...

Cell-permeable, small molecule agonist of TGR5 G-protein coupled receptor. This agonist has shown to increase glucagon like peptide-1 (GLP-1) secretion from primary intestinal cells.EZSolution™ TGR5...

Cell-permeable. A 10 mM (1 mg in 321 µl) solution of Thiazovivin (Cat. No. 1681-1) in anhydrous DMSO.EZSolution™ Thiazovivin is a 10 mM (1 mg in 321 µl) solution of Thiazovivin (Cat. No. 1681-1) in...

A 5 mM (1.56 mg in 1 ml), sterile-filtered solution of the enhancer of hESCs survival Thiazovivin (Cat. No. 1681) in anhydrous DMSO.EZSolution™ Thiazovivin, Sterile-Filtered is a 5 mM (1.56 mg in 1...

Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor (IC₅₀ = 37 nM). It raises high-density lipoprotein (HDL) cholesterol and reduces low-density lipoprotein (LDL) cholesterol levels...

A potent, selective and ATP-competitive mTOR inhibitor, with IC₅₀ values of 2 and 10 nM for mTORC1 and mTORC2 respectively; Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC₅₀ = 1800 nM)...

A potent, selective and ATP-competitive mTOR inhibitor (IC₅₀ = 2.1 nM for mTORC1). Torin 2 displays 800-fold selectivity for mTOR over PI3K (cellular EC₅₀ values of 0.25 nM and 200 nM, respectively)...

A 100 mM (25 mg in 538.1 µl) solution of Tozasertib (Cat. No. 1595-25) in anhydrous DMSO.EZSolution™ Tozasertib is a 100 mM (25 mg in 538.1 µl) solution of Tozasertib (Cat. No. 1595-25) in anhydrous...

EZSolution(TM) Triacsicn C, is an Inhibitor of acyl-CoA synthetase (IC₅₀ = 6.3 μM in Raji cells). Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer...

A 10 mM (1 mg in 330 µl) of Trichostatin A (Cat. No. 1606-1) in anhydrous DMSO.Trichostatin A (TSA) is a potent, reversible inhibitor of histone deacetylase.2271 | EZSolution™ Trichostatin A...

A 10 mM (5 mg in 1.43 ml), sterile-filtered solution of the RAR agonist TTNPB (Cat. No. 2776) in anhydrous DMSO.EZSolution™ TTNPB is a 10 mM (5 mg in 1.43 ml), sterile-filtered solution of the RAR...

A 10 mM (5.0 mg in 1.57 ml), sterile-filtered solution of the GSK-3β inhibitor TWS-119 (Cat. No. 1655) in anhydrous DMSO.EZSolution™ TWS-119 is a 10 mM (5.0 mg in 1.57 ml), sterile-filtered solution...

A 10 mM (1 mg in 264 µl) of potent Wnt signaling pathway inhibitor (Cat. No. 2063) in anhydrous DMSO.Wnt Antagonist, C59 is a potent Wnt signaling pathway inhibitor (IC₅₀ =

A potent, cell-permeable JAK2 inhibitor. A novel analog of the JAK2 inhibitor AG490 (Cat. No. 1570-5) that blocks STAT3 and phosphoinositide-3-kinase pathways. It is significantly more potent and...

A 10 mM (5 mg in 1550 µl) solution of Y-27632, Dihydrochloride (Cat. No. 1596-5) in deionized water.EZSolution™ Y-27632 is a 10 mM (5 mg in 1550 µl) solution of Y-27632, Dihydrochloride (Cat. No...

A 10 mM (3.20 mg in 1 ml) solution of the ROCK inhibitor Y-27632, Dihydrochloride (Cat. No. 1596) in deionized water.EZSolution™ Y-27632, Sterile-Filtered is a 10 mM (3.20 mg in 1 ml) solution of the...

A 10 mM (5 mg in 1.31 ml) solution of the potent JAK1 inhibitor ABT-494 (Upadacitinib) in anhydrous DMSO.ABT-494 (Upadacitinib) is a potent and selective Janus kinase JAK-1 inhibitor (IC₅₀ = 43 nM)...

A 10 mM (5 mg in 703 μl), sterile-filtered solution of the PDX1 inducer BRD-7552 (Cat. No. B2258) in anhydrous DMSO.EZSolution™ BRD-7552 is a 10 mM (5 mg in 703 μl), sterile-filtered solution of the...

Ezutromid is a first orally available drug for the treatment of Duchenne muscular dystrophy (DMD), a lethal, X-linked muscle wasting disease caused due to lack of dystrophin-a cytoskeleton protein...

K305 | EZViable Calcein AM Cell Viability Assay Kit Fluorometric DataSheet

F-Amidine (trifluoroacetate salt) is an irreversible inhibitor of protein arginine deiminase (PAD). The in vitro IC₅₀ values are 29.5 µM, 350 µM, and 21.6 µM for PAD1, PAD3 and PAD4, respectively...

F16 is a cell-permeable, fluorogenic, cationic, lipophilic mitochondrial toxin. Induces apoptosis as well as necrosis in tumor cells. Displays antitumor properties.F16 is a cell-permeable,...

Cell-permeable. A potent and irreversible FAAH (Fatty Acid Amide Hydrolase) inhibitor. Inhibits FAAH in a time-dependent manner by covalently modifying the enzyme's active site serine (IC₅₀ = 33 nM)...

Human Fatty Acid Binding Protein-s exhibit high affinity for small lipophilic ligands. Studies suggest that FABPs are involved in the uptake and metabolism of fatty acids, maintenance of Cellular...

5503 | FABP3 Antibody DataSheet

Human Fatty Acid Binding Protein-3 (FABP-3) exhibits high affinity for small lipophilic ligands. Studies suggest that FABPs are involved in the uptake and metabolism of fatty acids, maintenance of...

5504 | FABP4 Antibody DataSheet

FABPs have been reported to be involved in the uptake and metabolism of fatty acids, maintenance of Cellular membrane fatty acids levels, intraCellular trafficking, modulation of specific enzymes of...

FABPs have been reported to be involved in the uptake and metabolism of fatty acids, maintenance of Cellular membrane fatty acids levels, intraCellular trafficking, modulation of specific enzymes of...

5507 | FABP7 Antibody DataSheet

FABPs have been reported to be involved in the uptake and metabolism of fatty acids, maintenance of Cellular membrane fatty acids levels, intraCellular trafficking, modulation of specific enzymes of...

K364 | Factor IXa Activity Assay Kit Fluorometric DataSheet

Factor Va is a cofactor for the serine protease factor Xa, and in the presence of calcium ions they collectively assemble on a phospholipid surface to form the prothrombinase complex. The...

Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin...

Human factor VII is a single chain plasma glycoprotein, and is a zymogen in its native form. Proteolytic activation of factor VII, yields the enzyme factor VIIa, which when bound to the integral...

K358 | Factor VIIIa Activity Assay Kit Fluorometric DataSheet

Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a disulfide bond. Prior to secretion into plasma,...

K361 | Factor Xa Activity Fluorometric Assay Kit DataSheet

K362 | Factor Xa Inhibitor Screening Kit Fluorometric DataSheet

Factor Xa is a serine endoproteinase and a member of the S1 peptidase family. Factor Xa plays a critical role in the coagulation cascade by catalyzing the proteolytic conversion of prothrombin to...

K973 | Factor XIa Activity Assay Kit Colorimetric DataSheet

Human Factor XII is a single chain glycoprotein with a molecular weight of about 80,000. Once activated, principally from the action of kallikrein, Factor XII is converted into an active serine...

K994 | Factor XIIa Activity Assay Kit Colorimetric DataSheet

Human Factor -XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and prekallikrein are thought to be involved in a...

K522 | Factor XIIIa Activity Assay Kit Colorimetric DataSheet

K357 | FAD Colorimetric/Fluorometric Assay Kit DataSheet

3008 | FADD Antibody (Clone T1B) DataSheet

3039BP | FADD Blocking Peptide DataSheetAntibody Target: FADD Accession #: Q13158Gene ID: 8772Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate buffered...

Fadrozole is a potent, nonsteroidal aromatase inhibitor with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and...

3346 | FAF1 Antibody DataSheet

3346BP | FAF1 Blocking Peptide DataSheetAntibody Target: FAF1Accession #: Q9UNN5Gene ID: 11124Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

3399 | FAK Antibody DataSheet

FAK2 is a cytoplasmic tyrosine kinase involved in calcium-induced regulation of ion channels and activation of the MAP kinase signaling pathway. It regulates reorganization of the actin cytoskeleton,...

Famotidine is a competitive inhibitor of histamine H2-receptor located on the basolateral membrane of the parietal cells. Famotidine inhibits histamine-induced acid secretion in isolated canine...

Fangchinoline is a bisbenzylisoquinoline alkaloid that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown...

Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of FAS. Down regulates neuropeptide Y and Agouti-related...