CD11b Antibody| F40833-0.08ML/F40833-0.4ML/R31044

CD11b Antibody| F40833-0.08ML/F40833-0.4ML/R31044 | Gentaur UK, US & Europe Distribution

Background: CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: IHC, FACS, WB, ELISA

Application Details: IHC (Paraffin): 1:50-1:100, Flow Cytometry: 1:10-1:50, Western blot: 1:1000

Application Note: Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CD11b antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 253-282 from the human protein was used as the immunogen for this CD11b antibody.

Storage: Aliquot the CD11b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A