CD43 Antibody| F40339-0.08ML/F40339-0.4ML/R31521/V2258-20UG/V2258IHC-7ML

CD43 Antibody| F40339-0.08ML/F40339-0.4ML/R31521/V2258-20UG/V2258IHC-7ML | Gentaur UK, US & Europe Distribution

Background: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) [UniProt]

Format: Purified

Clone: 423CT7.9.2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgM

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:100-1:250

Application Note: Titration of the CD43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CD43 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 230-257 from the human protein was used as the immunogen for this CD43 antibody.

Storage: Aliquot the CD43 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A