(DANRE) dlc Antibody (C-Term) [ApR04884G]

(DANRE) dlc Antibody (C-Term) [ApR04884G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: Zf

Specificity: This DANRE dlc antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 557-591 amino acids from DANRE dlc.

Cellular Localisation: Membrane; Single-pass type I membrane protein

Molecular Weight: 72548

Clone: Polyclonal

Gene Name: dlc

Gene ID: 30120

Function: Acts as a ligand for Notch receptors and is involved in somitogenesis. Can activate Notch receptors. Required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.

Summary: Tissue Location: Strongly expressed in the early retina, where it precedes other delta proteins. Also expressed in cranial ganglia, in sensory epithelia including ear and lateral line and in scattered epidermal cells. In the mesoderm, expression is visible by 50% epiboly; it is expressed subsequently in the tail bud, in stripes in the presomitic mesoderm and in the posterior half of each somite. Also expressed in notochord, blood vessels and pronephros. In contrast to other delta proteins, it is not expressed in the majority of nascent primary neurons. In somites, it marks the posterior part of each formed somite, while deltaD (dld) marks the anterior part

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Delta-like protein C, DeltaC, delC, dlc