FUS Antibody| F40524-0.08ML/F40524-0.4ML

FUS Antibody| F40524-0.08ML/F40524-0.4ML | Gentaur UK, US & Europe Distribution

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: Bovine

Application: WB, IHC, FACS, IF, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:50-1:100, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50

Application Note: Titration of the FUS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This FUS antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 499-526 from the human protein was used as the immunogen for this FUS antibody.

Storage: Aliquot the FUS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A