Histone H3.3 Antibody (H3F3A)| F40711-0.08ML/F40711-0.4ML

Histone H3.3 Antibody (H3F3A)| F40711-0.08ML/F40711-0.4ML | Gentaur UK, US & Europe Distribution

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: DB, ELISA

Application Details: Dot blot: 1:500

Application Note: Titration of the Histone H3.3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Histone H3.3 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 1-30 from human H3F3A was used as the immunogen for this Histone H3.3 antibody.

Storage: Aliquot the Histone H3.3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A