IL-13 Antibody| F43210-0.08ML/F43210-0.4ML/R30541

IL-13 Antibody| F43210-0.08ML/F43210-0.4ML/R30541 | Gentaur UK, US & Europe Distribution

Background: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IF, IHC, ELISA

Application Details: Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This IL-13 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 118-146 from the human protein was used as the immunogen for this IL-13 antibody.

Storage: Aliquot the IL-13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A