Irak1 Antibody| F43845-0.08ML/F43845-0.4ML/R31305

Irak1 Antibody| F43845-0.08ML/F43845-0.4ML/R31305 | Gentaur UK, US & Europe Distribution

Background: Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Mouse

Predicted Spacies Reactivity: N/A

Application: WB, FACS, ELISA

Application Details: Western blot: 1:1000, Flow Cytometry: 1:10-1:50

Application Note: Titration of the Irak1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Irak1 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.

Storage: Aliquot the Irak1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A