KEAP1 Antibody| F40314-0.08ML/F40314-0.4ML/R32225

KEAP1 Antibody| F40314-0.08ML/F40314-0.4ML/R32225 | Gentaur UK, US & Europe Distribution

Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Format: Purified

Clone: 297CT6.1.6

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgM, k

Species Reactivity: Human

Predicted Spacies Reactivity: Pig

Application: WB, ELISA

Application Details: Western blot: 1:100

Application Note: Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This KEAP1 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.

Storage: Aliquot the KEAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A