NEDD9 Antibody| F43986-0.08ML/F43986-0.4ML/R31702

NEDD9 Antibody| F43986-0.08ML/F43986-0.4ML/R31702 | Gentaur UK, US & Europe Distribution

Background: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B-and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the NEDD9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This NEDD9 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 335-363 from the human protein was used as the immunogen for this NEDD9 antibody.

Storage: Aliquot the NEDD9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A