Description
SBI-797812 is a novel nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 acts as a “super catalyst” that more efficiently generates NMN (nicotinamide mononucleotide).
SBI-797812 is a novel nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 acts as a “super catalyst” that more efficiently generates NMN (nicotinamide mononucleotide).
Alternate Name/Synonyms: 1-(4-(((1R,5S)-8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)sulfonyl)phenyl)-3-(pyridin-4-ylmethyl)urea
Appearance: Crystalline solid
Formulation:
CAS Number: 2237268-08-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₂₂N₄O₄S
Molecular Weight: 402.47
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >50 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A novel NAMPT activator
MDL Number:
PubChem CID: 135222620
SMILES: C1CC2CN(CC1O2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)NCC4=CC=NC=C4
InChi: InChI=1S/C19H22N4O4S/c24-19(21-11-14-7-9-20-10-8-14)22-15-1-5-18(6-2-15)28(25,26)23-12-16-3-4-17(13-23)27-16/h1-2,5-10,16-17H,3-4,11-13H2,(H2,21,22,24)
InChi Key: KTSOHNHLOLGQCY-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |