Sulfo-NHS | 2321

KEY FEATURES: • Sulfo-NHS assists in stabilizing the protein-EDC intermediate, thus allowing for a more efficient crosslinking reaction. • Water-soluble; can be used under physiologic conditions • Assists in converting carboxyl groups to sulfo-NHS esters which react with primary amines APPLICATIONS: • Increases the efficiency of EDC-mediated coupling reactions • Useful for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticles • Assists in converting carboxyl groups to primary amine-reactive sulfo-NHS esters

Sulfo-NHS is a sulfonated derivative of N-hydroxysuccinimide (Cat. No.2331) that is used as a catalyst in the zero-length crosslinking of proteins

2321 | Sulfo-NHS DataSheet

Alternate Name/Synonyms: Hydroxy-2,3-dixopyrrolidine-3-sulfonic acid sodium salt; Sulfo-NHS; SNHS; N-Hydroxysulfosuccinimide sodium salt

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 106627-54-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄H₄NNaO₆S

Molecular Weight: 217.13

Cell-Permeable?: No

Purity: ≥95% by NMR

Solubilities: H₂O (~ 2 mg/ml)

Handling: Protect from moisture

Country of Origin: USA

Tag Line: A useful catalyst in the zero-length crosslinking of proteins

MDL Number: MFCD00043100

PubChem CID: 3520574

SMILES: C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]

InChi: InChI=1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1

InChi Key: RPENMORRBUTCPR-UHFFFAOYSA-M