TFAM Antibody| F40574-0.08ML/F40574-0.4ML/R31036

TFAM Antibody| F40574-0.08ML/F40574-0.4ML/R31036 | Gentaur UK, US & Europe Distribution

Background: This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: IHC, FACS, IF, WB, ELISA

Application Details: IHC (Paraffin): 1:50-1:100, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000

Application Note: Titration of the TFAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TFAM antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 216-246 from the human protein was used as the immunogen for this TFAM antibody.

Storage: Aliquot the TFAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A