TLR2 Antibody| F44370-0.08ML/F44370-0.4ML/R32649/RQ4761/V2896-20UG

TLR2 Antibody| F44370-0.08ML/F44370-0.4ML/R32649/RQ4761/V2896-20UG | Gentaur UK, US & Europe Distribution

Background: TLR2 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Primate

Application: WB, IHC, FACS, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50, Flow Cytometry: 1:10-1:50

Application Note: Titration of the TLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TLR2 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 212-242 from the human protein was used as the immunogen for this TLR2 antibody.

Storage: Aliquot the TLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A