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3893BP | DKK3 Blocking Peptide DataSheetAntibody Target: DKK3 Accession #: NP_612528Gene ID: 171548Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3894BP | DKK4 Blocking Peptide DataSheetAntibody Target: DKK4 Accession #: NP_663567Gene ID: 234130Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) is a useful substrate for the enzyme 3-hydroxyl-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase. HMG-CoA is the key intermediate in the biosynthsis...

DL-Aminoglutethimide is a derivative of the sedative glutethimide. It acts as an aromatase inhibitor (IC₅₀ = 7.5 µM). Blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of...

K743 | DL-Serine Assay Kit Fluorometric DataSheet

DLD (Dihydrolipoamide dehydrogenase), also known as GCSL (glycine cleavage system L protein), is a component of the glycine cleavage system as well as of the alpha ketoacid dehydrogenase complexes...

3715 | DMAP1 Antibody DataSheet

3715BP | DMAP1 Blocking Peptide DataSheetAntibody Target: DMAP1Accession #: Q9NPF5Gene ID: 55929Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

DMH-1 is an analog of Dorsomorphin (Cat. No. 1686) that acts as a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH-1 exclusively targets the BMP but not the VEGF pathway. Blocks...

A cell-permeable prolyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic...

3844 | Anti-DMP1 Antibody DataSheet

3844BP | DMP1 Blocking Peptide DataSheetAntibody Target: DMP1 Accession #: EDL99499Gene ID: 25312Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

DMSO is a highly polar aprotic organic solvent. It is widely used to dissolve both polar and nonpolar compound. It penetrates biological membranes and is used as a vehicle for topical application of...

DMXAA acts as a tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core. It potently activates the TANK-binding kinase 1-interferon...

DNA Binding Protein-7 (DBP-7) is a N-terminal His-tagged recombinant protein and a member of the Sso7d family of small, abundant, non-specific DNA-binding proteins from the hyperthermophilic Archea...

3933 | DNA Binding Protein-7 (DBP-7) Antibody DataSheet

DNA Cleanup Maxi Kit | K1369

K253 | DNA Damage Quantification Colorimetric Kit DataSheet

Dichlone, a popular pesticide and fungicide, acts as a potent DNA methylation inhibitor (EC₅₀ = 460 nM against Dnmt3A/3L catalytic complex). Dichlone efficiently reactivates YFP gene expression in a...

6110 | DNA Methyltransferase 1 (Clone 60B1220.1) Antibody DataSheet

6113 | DNA Methyltransferase 3a (Clone 64B814.1) Antibody DataSheet

DNA Ploidy Analysis Staining Kit | K1439

DNA Polymerase I Large (Klenow) Fragment is the large fragment of E. coli DNA Polymerase IM1212 | DNA Polymerase I Large (Klenow) Fragment DataSheetSort Name: DNA Polymerase I Large (Klenow)...

The Large, Klenow Fragment is a proteolytic product of E. coli DNA Polymerase I, which retains 5’→ 3’ polymerase activity and 3’→ 5’ exonuclease activity. It is useful for generating...

K539 | DNA Quantification Assay Kit Fluorometric DataSheet

3130 | DNA-PK Antibody DataSheet

K429 | DNAse I Activity Assay Kit Fluorometric DataSheet

3214 | DNase I Antibody DataSheet

Deoxyribonuclease I (DNase I) is a non-specific endonuclease that catalyzes the cleavage of phosphodiester bonds in single/double-stranded DNA, chromatin, and RNA:DNA hybrids to generate di-and/or...

3946 | DNMT1 Antibody DataSheet

3946BP | DNMT1 Blocking Peptide DataSheetAntibody Target: DNMT1Accession #: NP_445806.3Gene ID: 84350Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K4195 | DNMT1 Human Elisa Kit DataSheet

3488 | Dnmt2 Antibody DataSheet

6848 | DNMT2 polyclonal antibody DataSheet

3227 | DNMT3a Antibody DataSheet

3227BP | DNMT3a Blocking peptide DataSheetAntibody Target: DNMT3aAccession #: Q9Y6K1Gene ID: 1788Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

6849 | DNMT3A polyclonal antibody DataSheet

3275 | DNMT3b Antibody DataSheet

Antibody Target: DNMT3bAccession #: Q9UBC3Gene ID: 1789Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50%...

dNTP mix is a premixed solution containing the sodium salts of dATP. dCTP, dGTP, and dTTP, each at a concentration of 2.5 mM in H₂O; the total concentration of nucleotides, therefore, is 10 mM (pH 7...

An anticancer agent. Docetaxel binds to microtubules reversibly with high affinity and prevents microtubule depolymerization and disassembly in the absence of GTP. Used mainly for the treatment of...

A nonionic detergent for membrane protein stabilization and crystallization (CMC = 100 - 600 µM).Dodecyl-β-D-maltopyranoside is a nonionic detergent for membrane protein stabilization and...

Dofetilide is a class III antiarrhythmic agent and inhibits the rapid delayed rectifier K⁺current (IKr) with IC₅₀values of 31.5 nM in guinea pig cardiomyocytes. At higher doses it demonstrates...

Donepezil is a potent acetylcholinesterase (AChE) inhibitor with an IC₅₀ value of 5.7 nM. It produces a significant increase in acetylcholine content in rat cerebral cortex at a dose of 5 mg/kg (po)...

K4219 | Dopamine DA Elisa Kit DataSheet

Cell-permeable. A potent protein kinase inhibitor with a >330-fold selectivity for p38 MAPK compared with 12 other protein kinases. In contrast to other p38 MAPK inhibitors (e.g., SB203580),...

Doripenem is a broad-spectrum β-lactam antibiotic. It is active against Gram-negative and Gram-positive bacteria, including S. aureus, S. pneumoniae, E. coli, and K. pneumoniae. Doripenem reduces the...

A water-soluble derivative of the potent, reversible, AMPK inhibitor Dorsomorphin (Cat. No.1686).Dorsomorphin dihydrochloride is a potent, selective , reversible and ATP-competitive inhibitor of...

Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 µM ATP and no AMP). Does not affect the...

Dorzolamide Hydrochloride is an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate...

The tissue grinder is used for homogenizing delicate tissues (such as intestines, liver, and heart) and cells. Designed for hand operation. Hollow handle permits packing with ice. Grinder also...

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13...

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitorDovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitorB1614 | Dovitinib DataSheetAlternate Name/Synonyms: Dovitinib, CHIR-258; CHIR...

Doxifluridine is a fluoropyrimidine derivative that acts as an oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid...

Anti-tumor antibiotic. Inhibitor of Reverse transcriptase and RNA Polymerase. Immunosuppressive agent. Highly effective myotoxin that inhibits topoisomerase II. Binds to Nucleic acids, presumably by...

E4613 | Doxycycline Elisa Kit DataSheet

A synthetic derivative of oxytetracycline. Acts as a broad spectrum antibiotic and matrix metallo-proteinases (MMP) inhibitor. Useful in studies involving wound healing and tissue remodeling...

DP-4978 is a potent and selective pan-RAF inhibitor with potential anticancer activity. DP-4978 displays activities against B-Raf or Ras mutant tumor cells. It binds to A-Raf, B-Raf and C-Raf...

The DpnI restriction enzyme digests DNA. DNA purified from a dam+ E. coli strain will be a substrate for DpnI due to the adenine methylation.M1236 | DpnI DataSheetSort Name: DpnILabel Name:...

Cell-permeable. A potent, slow binding dipeptidyl peptidase IV inhibitor with IC₅₀ values of 3, 5, 8, and 8 nM for rat, canine, human and monkey enzymes respectively. Acts as a long-acting...

A potent, selective, reversible, and slow binding dipeptidyl peptidase IV inhibitor (IC₅₀ = 14 nM). Displays >15,000 fold selectivity over DPP-II and a range of Proline-cleaving proteases. Displays...

DPP IV Mouse Elisa Kit | K4770

DPP IV/CD26 human Elisa Kit | K4801

3898 | DPP10 Antibody DataSheet

3898BP | DPP10 Blocking Peptide DataSheetAntibody Target: DPP10 Accession #: AAH63074.4Gene ID: 269109Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K779 | DPP4 Activity Fluorometric Assay Kit DataSheet

K780 | DPP4 Inhibitor Screening Kit Fluorometric DataSheet

DPP4, dipeptidyl peptidase-4 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. DPP4...

3826BP | DPPA4 Blocking Peptide DataSheetAntibody Target: DPPA4Accession #: Q7L190Gene ID: 55211Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) DPPA4 peptide in...

6693 | DPPIV (Human) Antibody DataSheet

Cell-permeable. A potent, specific, and competitive transition-state substrate analog inhibitor of dipeptidyl peptidase IV (DPPIV) (Ki =130 nM). May be used in cell cuture (1-10 μM) or Experimental...

6694 | DPPIV (Mouse) Antibody DataSheet

Cell-permeable. A very potent poly(ADP-ribose) polymerase (PARP) inhibitor.DPQ is a very potent poly(ADP-ribose) polymerase (PARP) inhibitor.1899 | DPQ DataSheetAlternate Name/Synonyms:...

DprE1-IN-2 is a potent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) of Mycobacterium tuberculosis, an essential enzyme involved in cell wall metabolism, for which new promising...

DPVP a derivative of Resveratrol (Cat. No. 1758). DPVP is an inhibitor of FAS expression and also has shown to inhibit 3T3-L1 adipocyte differentiation with IC₅₀ values of 13.5 µM.DPVP a derivative...

A potent, brain-penetrant, and water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor. IC₅₀ values are 0.20 and 0.24 µM for PARP-1 and PARP-2 respectively. Neuroprotective in vitro and in vivo...

3057 | DR3 (Death Receptor 3/Apo3) Polyclonal Antibody DataSheet

3057R | DR3/Apo3 Antibody DataSheet

3057RBP | DR3/Apo3 Blocking Peptide DataSheetAntibody Target: DR3/Apo3 Accession #: AAH17526 Gene ID: 85030Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3061A | DR4 Antibody DataSheet

3061BP | DR4 Blocking Peptide DataSheetAntibody Target: DR4 Accession #: EAW63636.1Gene ID: 8797Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3062 | DR5 Antibody DataSheet

Antibody Target: DR5 Accession #: Q13133Gene ID: 21933Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1%...

3216R | DR6 Antibody DataSheet

3216RBP | DR6 Blocking Peptide DataSheetAntibody Target: DR6Accession #: EDL23398.1Gene ID: 94185Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3216 | DR6 Polyclonal Antibody DataSheet

5075 | DRAM Antibody (NT) DataSheet

DREADD agonist 21 is a potent muscarinic hM3Dq DREADD agonist (EC₅₀ = 1.7 nM).DREADD agonist 21 is a potent muscarinic hM3Dq DREADD agonist (EC₅₀ = 1.7 nM).B1924 | DREADD Agonist 21...

Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 with IC₅₀ values of 16.9, 2.47 and 1.46 μM, respectively. Droxinostat sensitizes cells to apoptosis by decreasing c-FLIPL and c-FLIPS...

offers miRNA negative control for miRNA experiments. The miRNA Negative Control has no homology to any known microRNA or mRNA sequences and thus ensures the specificity of the experiment.M1263 | ds...

offers miRNA mimics, which are RNA oligonucleotides designed to mimic endogenous mature microRNAs (miRNAs) for use in miRNA function research. Each microRNA mimics includes one strand that is...

DSDP is a human STING agonist. It induces proinflammatory cytokine response in a human STING-dependent manner. DSDP does not have any effect on mouse STING.DSDP is a human STING agonist. It induces...

DSM265 is a potent, selective and long duration dihydroorotate dehydrogenase (DHODH)) inhibitor (IC₅₀ = 8.9 nM). DSM265 is potential useful for the prevention and treatment of malaria. DSM265 is...

The recombinant RFP (dsRed) was expressed and purified from transformed E. coli using a method that ensures high purity and maximal RFP fluorescence. Endotoxin was removed, so the protein is suitable...

DTBA is a novel biological reducing reagent with enhanced properties over other commonly used reagents. DTBA has been shown to reduce small molecule disulfides 3-5-fold faster than DTT (Cat. No...

A useful reagent for maintaining sulfhydryl groups in the reduced stateDTE is a useful reagent for maintaining sulfhydryl groups in the reduced stateB2410 | DTE DataSheetAlternate Name/Synonyms:...

DTP3 is a potent and selective GADD45β/MKK7 inhibitor, that inhibits cancer-selective NF-kB survival pathway. DTP3 specifically kills MM cells, ex vivo and in vivo, ablating MM xenografts in mice,...

KEY FEATURES & APPLICATIONS: • Water-soluble • Has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends • Contains cleavable, 8-atom (12 Å) spacer arm • The disulfide...

An excellent reagent for maintaining SH groups in reduced state. DTT quantitatively reduces disulfides. It is effective in sample buffers for reducing protein disulfide bonds prior to SDSPAGE.DTT is...

A useful reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE.DTT is a...