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K590 | Fructose-1,6-Bisphosphatase Activity Assay Kit Colorimetric DataSheet

Fruquintinib (HMPL-013) is a potent and selective vascular endothelial growth factor receptors1/2/3 (VEGFR 1/2/3) inhibitor with IC₅₀s of 33, 0.35, and 35 nM, respectively. It only weakly inhibits...

A1062 | FSCN1 Monoclonal Antibody DataSheet

Human FSH is a glycoprotein produced from urine of post-menopausal women and having a total molecular mass of 35,500 Dalton. hFSH is a heterodimeric hormone consisting of 165 amino acids chain...

FTI-277 is a potent and selective farnesyltransferase (FTase) inhibitor (IC50 = 0.5 nM). It potently inhibits (IC₅₀ = 100 nM) H-Ras, but not the geranylgeranylated Rap1A processing in whole cells...

6699 | FTO Antibody (Clone FT86-4) DataSheet

6764 | FTO Antibody (NT) DataSheet

K4921 | FTO human intracellular Elisa Kit DataSheet

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO...

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO...

Fucoxanthin is a natural pigment found in microalgae, especially diatoms and Chrysophyta. Recently, it has been shown to have antioxidant, anti-inflammatory, anti-tumor, and anti-obesity activity in...

Fulvestrant is a high affinity estrogen receptor antagonist (IC₅₀ = 0.29 nM), that works by down-regulating and degrading the estrogen receptor, ERα. Reported to lack any partial agonist activity...

Fumagillin is a meroterpenoid antibiotic isolated from Aspergillus fumigatus. An anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of...

K596 | Fumarase Activity Colorimetric Assay Kit DataSheet

K633 | Fumarate Colorimetric Assay Kit DataSheet

Funalenone, a phenalene compound isolated from mycelium of Aspergillus niger FO-5904, acts as an inhibitor of type I collagenase (MMP-1). Funalenone inhibits 50% of type I collagenase activity at a...

K1415 | Fungal Genomic DNA Kit DataSheet

A cell-permeable, fluorescent Calcium (Ca²⁺) indicator. Selective for Ca2+ over other divalent cations Mg²⁺, Zn²⁺, Fe²⁺ and Mn²⁺. Useful for measuring intracellular Ca²⁺ concentration.FURA-2 AM is a...

Fura-4F AM is a fluorescent intracellular ratiometric calcium indicator analog of FURA-2 (Cat. No. 2243) for detection of higher Ca²⁺ concentrations. lmax: 370± 3 nm (EtOAc); lem: 475± 4 nm (EtOAc)...

FURA-5F/AM is a fluorescent cell membrane-permeant form of FURA-2 (Cat. No. 2243) that can be loaded into the cell where it is hydrolysed by cytosolic esterases and trapped as the active chelator. ...

Furamidine dihydrochloride is a potent, selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor (IC₅₀ = 9.4 μM). Displays selectivity over PRMT5, PRMT6 and CARM1 (IC50...

K4231 | Furazolidone Elisa Kit DataSheet

Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA, which leads to the gradual inhibition of monoamine oxidase (MAO). It is used...

Furin is a member of the proprotein convertase family. As a cellular protease, Furin processes various latent precursor proteins into their biologically active products by cleaving at the RX(K/R)R...

3873 | Furin/PACE Antibody DataSheet

3873BP | Furin/PACE Blocking Peptide DataSheetAntibody Target: Furin/PACEAccession #: NP_035176Gene ID: 18550Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Fusicoccin is a toxin originally extracted from Fusicoccum amygdali DelFusicoccin is a toxin originally extracted from Fusicoccum amygdali DelB1625 | Fusicoccin DataSheetAlternate Name/Synonyms:...

Fusidic Acid is a bacteriostatic antibiotic derived from the fungus Fusidium coccineum that acts as a bacterial protein synthesis inhibitor by preventing the turnover of elongation factor G (EF-G)...

FX1 is a potent B cell lymphoma 6 (BCL6) inhibitor. FX1 displays 10-fold greater potency than endogenous corepressors and binds an essential region of the BCL6 lateral groove. FX1 disrupts formation...

G-749 is a potent FLT3 kinase inhibitor that displays potent and sustained inhibition of the FLT3 wild type and mutants including FLT3-ITD, FLT3-D835Y, FLT3-ITD/N676D, and FLT3-ITD/F691L in cellular...

5094 | G-CSF Antibody DataSheet

5094RBP | G-CSF Blocking Peptide DataSheetAntibody Target: G-CSF Accession #: NP_757373 Gene ID: 1440Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

Granulocyte Colony stimulating Factor (G-CSF) is a potent stimulator of bone marrow cells, especially those of neutrophil lineage. In addition, G-CSF can enhance the survival and activate the...

G-CSF is a potent stimulator of bone marrow cells, especially those of neutrophil lineage. In addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils...

E4287 | G1/S-specific cyclin-D1 CCND1 Human Elisa Kit DataSheet

3619 | G3BP Antibody DataSheet

3619BP | G3BP Blocking Peptide DataSheetAntibody Target: G3BP Accession #: Q13283Gene ID: 10146Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

Aminoglycoside antibiotic related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely...

Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD...

3250R | Ga15/16 Antibody DataSheet

3250RBP | Ga15/16 Blocking Peptide DataSheetAntibody Target: Ga15/16 Accession #: AAC25612Gene ID: 2769Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3524 | GAAP Antibody DataSheet

3524BP | GAAP Blocking Peptide DataSheetAntibody Target: GAAPAccession #: P55061Gene ID: 7009Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

Gabexate is an inhibitor of serine proteases. It inhibits plasma kallikrein, thrombin, plasmin, factor Xa with Ki values of 0.2 μM, 0.97 μM, 1.6 μM and 8.5 μM. It exerts an anticoagulant effect on...

Human gAcrp30 (amp-1) also known as Adipolean is a 16.6 kDa protein that corresponds to the C-terminal globular domain of adiponectin (amp-1). gAcrp30/Adipolean is expressed and secreted exclusively...

Murine gAcrp30 is a 16.6 kDa protein originating from a proteolytic cleavage of Acrp30 (adipocyte complement-related protein of 30 kDa). Research shows that gAcrp30 is more active than the full...

Rat gAcrp30 (amp-1) is a 16.6 kDa protein that corresponds to the C-terminal globular domain of adiponectin (amp-1). gAcrp30/Adipolean is expressed and secreted exclusively by adipose tissue. This...

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production...

3421 | GADD153 Antibody DataSheet

3421BP | GADD153 Blocking Peptide DataSheetAntibody Target: GADD153 Accession #: P35638Gene ID: 1649Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3249 | Gai2 Antibody DataSheet

3249BP | Gai2 Blocking Peptide DataSheetAntibody Target: Gai2 Accession #: AAM12620Gene ID: 2771Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K617 | Galactose and Lactose Colorimetric/Fluorometric Assay Kit DataSheet

K621 | Galactose Colorimetric/Fluorometric Assay Kit DataSheet

Galantamine is an alkaloid originally isolated from the bulbs and flowers of various Galanthus species. It inhibits acetylcholinesterase with an IC₅₀ of 800 nM. It is a potent allosteric potentiating...

3596 | Galectin-1 Antibody DataSheet

Galectin-1 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of -galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs)...

Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and...

3591 | Galectin-3 Antibody DataSheet

3591BP | Galectin-3 Blocking Peptide DataSheetAntibody Target: Galectin-3Accession #: P08699Gene ID: 83781Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

Lectins are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with -galactoside...

LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds betagalactosidemresidues. This protein is secreted from cells by ectocytosis, which is...

Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The galectins are a family of beta-galactosidase-binding proteins...

5647 | Galectin-7 Antibody DataSheet

Galectin-7 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of -galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs)...

Galectin-8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific...

Galectin-8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific...

3827 | Galectin-9 Antibody DataSheet

3827BP | Galectin-9 Blocking Peptide DataSheetAntibody Target: Galectin-9 Accession #: O00182Gene ID: 3965Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) Galectin-9...

Galectin-9 (Gal-9) is a member of animal lectins that have an affinity to beta-galactosides and Forssman pentasaccharide. It is strongly overexpressed in Hodgkin's disease tissue and it might...

Galiellalactone is a fungal metabolite that inhibits IL-6-mediated JAK/STAT signal transduction in HepG2 cells (IC₅₀ = 0.25-0.5 μM). The selectivity of this compound is achieved by its ability to...

Gallein | B3391Description: Gallein is an inhibitor of G protein βγ subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells. It...

Galloflavin is a lactate dehydrogenase (LDH) inhibitor inhibiting both LDH-A and LDH-B isoforms of the enzyme with Ki values of 5.46 a µM and 15.06 µM, respectively. It blocks the proliferation of...

Polypeptide N-acetylgalactosaminyltransferase 16 (GalNAc-T16) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues. Twenty...

Polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues. Twenty...

Polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues. Twenty...

Polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues, and was...

Gambogic acid is a plant-derived natural product that acts as a caspase activator and apoptosis inducer, which causes an irreversible arrest in the G2/M phase of the cell cycle. It causes a decrease...

K784 | Gamma Glutamyl Transferase GGT Activity Colorimetric Assay Kit DataSheet

K785 | Gamma Glutamyl Transferase GGT Activity Fluorometric Assay Kit DataSheet

An acyclic analog of the nucleoside guanosine, chemically related to acyclovir. It inhibits the replication of viruses including CMV, Herpes Simplex, Varicella Zoster and Epstein-Barr. It inhibits...

Ganetespib (STA-9090) is a non-Geldanamycin, selective Hsp90 inhibitor that displays antineoplastic activity. downregulates VEGFR, c-MET, HER2, IGF-IR, EGFR, and other Hsp90 client proteins involved...

Ganoderic Acid is a triterpene found in Ganoderma mushrooms, commonly used in Traditional Chinese Medicine. Ganoderic Acid is reported to display anti-tumor activity mediated through its inhibitory...

Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC₅₀ ~ 5 µM in...

Cell-permeable. A Hedgehog (Hh) signaling pathway antagonist. Inhibits Hh signaling downstream of Smo and Sufu at the level of Gli (IC₅₀ = 5 µM). GANT61 has also been shown to inhibit the in vitro...

K680 | GAPDH Activity Assay Kit DataSheet

3777RBP | GAPDH Blocking Peptide DataSheetAntibody Target: GAPDH Accession #: XP_214281.3Gene ID: 290604Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a catalytic enzyme commonly known to be involved in glycolysis. The enzyme exists as a tetramer composed of 36-kDa subunits and has various...

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) is a catalytic enzyme normally known to play a role in glycolysis. GAPDH exists as a tetramer composed of 36-kDa subunits and has a range of...

Gapdh, also known as glyceraldehyde 3-phosphate dehydrogenase, is an enzyme of 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules...

Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a potent inhibitor of histone acetyltransferases (HATs) p300 (IC50 = 7 µM) and PCAF (IC50 = 5 µM) both in...

A selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-κB in HEK 293 cells expressing TLR7. Activates TLR8 only at high concentrations (3µg/ml). Gardiquimod...

Garenoxacin is a potent des-F(6)-quinolone antibacterial agent and a topoisomerase II inhibitor.Garenoxacin is a potent des-F(6)-quinolone antibacterial agent and a topoisomerase II inhibitor.B2457 |...

K4220 | GARS Human Elisa Kit DataSheet

Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF- binding protein that contains multiple protease inhibitor structural domains. It is expressed...

GBR-12909 is a potent and selective inhibitor of dopamine uptake (Ki = 1 nM). It inhibits dopamine uptake in tissue slices obtained from rat neostriatum at nanomolar concentrations. GBR-12909 (10...

GBR-12935 is a potent and selective dopamine reuptake inhibitor.GBR-12935 is a potent and selective dopamine reuptake inhibitor.B1998 | GBR-12935 DataSheetAlternate Name/Synonyms: 1-(2...

GTB-440 is a modulator of sickle hemoglobin S (HbS). It binds to the N‐terminal valine of one of the haemoglobin α chains and increases HbS affinity for oxygen. GBT440 dose‐dependently increases HbS...

3153 | GCK (Glucokinase) Antibody DataSheet

GCP-2 is a connective tissue derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. GCP-2 selectively attracts neutrophils and has also been shown to exert angiogenic activity...