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meta-Topolin is an aromatic cytokinin, first isolated from leaves of Populus x robusta. Cytokinins (CTKs) are a class of growth-regulating hormones involved in various physiological and developmental...

Metergoline is a serotonin (5-HT) receptor antagonist. It is active at 5-HT1 (pKi=7.8 for 5-HT1B), 5-HT2 (pKi=8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C respectively) and 5-HT7 (pKi=16 nM)...

An anti-diabetic agent. It reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by...

Methylseleninic acid is an organoselenium compound that has a role as a human xenobiotic metabolite, histone deacetylase inhibitor and an antineoplastic agent. MSA displays anticancer activity...

K898 | Methanol Assay Kit Colorimetric DataSheet

Methazolamide is a potent carbonic anhydrase (CA) inhibitor (IC50 = 130 nM) with anti-glaucoma, anti-diabetic, and potential anti-neoplastic activity. It reduces intraocular pressure and...

K442 | Methionine Assay Kit Fluorometric DataSheet

Methionine-Enkephalin ELISA Kit | E5098-100Description: Methionine enkephalin (MEK) is an opioid peptide composed of five amino acids with multiple biological activities. MEK is prominent in...

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division...

Methoxy-X04 is a derivative of Congo Red (Cat. No. 2588) and Chrysamine G that acts as a fluorescent probe for the detection of amyloid self-assembly in vitro and in vivo. It stains plaques, tangles,...

6124 | Methyl Lysine (Biotin) Antibody DataSheet

Methyl-β-cyclodextrin is a randomly methylated form of β-cyclodextrin. Methyl-β-cyclodextrin has been used to improve the aqueous solubility of various compounds as well as to extract cholesterol...

K500 | Methylglyoxal Assay Kit Colorimetric DataSheet

Methylstat is a methyl ester prodrug that inhibits Jumonji C domain-containing histone demethylase (JMJD) in cells. Methylstat inhibits growth of JMJD2C-sensitive oesophageal carcinoma cell line...

K986 | Methyltransferase Activity Assay Kit Colorimetric DataSheet

K521 | Methyltransferase Activity Assay Kit Fluorometric DataSheet

Metoclopramide is a 5-hydroxytryptamine (serotonin) 5-HT3 receptor antagonist and dopamine D2 receptor antagonist. Metoclopramide inhibits 5-HT3 receptor and Dopamine D2 receptor binding affinity...

Metronidazole is a nitroimidazole compound that acts as an antiprotozoal drug but it is also active against bacteria. Used to treat bacterial, fungal and parasitic infections.Metronidazole is a...

A HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitor. Cholesterol lowering drug. Inhibits the biosynthesis of isoprenoids; induces apoptosis by inhibition of post-translational...

MF-438 is a potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC₅₀ of 2.3 nM.MF-438 is a potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC₅₀...

A potent, reversible proteasome inhibitor with Ki of 21 nM for 20S proteasome and 35 nM for 26S proteasome. The inhibition of proteasome was through specific inhibition of chymotrypsin-like activity...

A cell-permeable, potent, and reversible proteasome inhibitor (Ki = 4 nM). Reduces degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast by the 26S complex...

MGCD0103 (Mocetinostat) is a class I selective HDAC inhibitor that inhibits HDAC1, HDAC2 and HDAC3 with IC₅₀ values of 0.15, 0.29 and 1.66 µM, respectively. Displays anticancer activities.MGCD0103...

A selective thyroid hormone receptor β agonist with EC₅₀ values of 0.21 and 3.74 µM for THRβ and THRα, respectively. It significantly lowers non-HDL-C and liver TG in hypercholesterolemic rat and...

3820 | mgMT Antibody DataSheet

3820BP | MGMT Blocking Peptide DataSheetAntibody Target: MGMT Accession #: P24528Gene ID: 25332Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

K4196 | MGMT Human Elisa Kit DataSheet

MHP is a synthetic activator of sphingosine kinase (SPHK1); significantly stimulates CAMP mRNA and protein production in ketatinocytes (KC).MHP is a synthetic activator of sphingosine kinase (SPHK1);...

MHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. Treatment with MHY1485 suppresses the basal autophagic flux, and this...

MI-2 is a Menin-MLL (Mixed linage leukemia) protein interaction inhibitor with an IC₅₀ of 0.45 μM. MLL protein is a histone methyltransferase that positively regulates gene transcription. However,...

MI-3 is a Menin-MLL (Mixed linage leukemia) protein interaction inhibitor with an IC₅₀ of 648 ± 25 nM. MLL protein is a histone methyltransferase that positively regulates gene transcription...

MI-463 is a potent inhibitor of Menin-MLL interaction (IC₅₀ = 15.3 nM). Pharmacologic inhibition of the menin-mLL interaction substantially delays progression of mLL leukemia in murine models through...

MI-773, also known as SAR405838, is a spiro-oxindole that acts as a highly potent and selective MDM2 inhibitor. MI-773 binds to MDM2 with a Ki value of 0.88 nM and blocks the MDM2-p53 interaction. It...

MI-nc (hydrochloride) is a weak inhibitor of the menin-MLL interaction. Menin is a tumor suppressor protein. Menin is a part of the MLL (Mixed Lineage Leukemia) SET1-like histone methyl transferase...

MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3...

MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2 is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases...

Micafungin is an antifungal drug that belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component...

A hepatotoxic cyclic heptapeptide toxin produced by cyanobacteria. A selective inhibitor of protein phosphatase 1 (PP1) (IC₅₀ = 1.7 nM) and protein phosphatase 2A (PP2A) (IC₅₀ = 0.04 nM). Less...

K249 | Microsome Isolation Kit DataSheet

5479 | Midkine Antibody DataSheet

Human Midkine (MK) is a new member of the heparin-binding neurotrophic factor family. MK and PTN (Pleiotrophin) are structural homologs, and are highly conserved among species. MK plays important...

Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an...

A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. Acts as an allosteric MIF (macrophage migration inhibitory factor) inhibitor. It occupies an...

5571 | MIF Antibody DataSheet

5571BP | MIF Blocking Peptide DataSheetAntibody Target: MIF Accession #: CAG46452Gene ID: 4282Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

MIF human Elisa Kit | K4786

The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF...

Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor...

Progesterone receptor antagonist; stimulates prolactin secretion. Also acts as Pgp inhibitor.Mifepristone is a progesterone receptor antagonist; stimulates prolactin secretion. Also acts as Pgp...

Human MIG (monokine induced by interferon ) is produced by microphages and other cells. It is a member of the chemokine family (C-X-C) of cytokines. MIG acts as a chemoattractant toward monocytes,...

Murine MIG (monokine induced by interferon ) is produced by microphages and other cells. It is a member of the chemokine family (C-X-C) of cytokines. MIG acts as a chemoattractant toward monocytes,...

MIG, a CXC chemokine, is produced by IFN- stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also...

Migalastat hydrochloride is a pharmacological chaperone that acts as a selective and competitive inhibitor of α-galactosidase (IC₅₀ = 40 nM). At subinhibitory concentrations,...

An α-glucosidase inhibitor which induces an enhanced and prolonged release of glucagon-like peptide-1, regulating appetite and stabilizing body weight in humans. Displays anti-atherothrombotic effect...

Miglustat is an inhibitor of the N-linked oligosaccharide processing enzymes α-glucosidase I and II. It inhibits rat testicular enzymes ceramide-glucosyltransferase and β-glucosidase 2 with IC50...

Cell-permeable. A potent, cAMP-specific phosphodiesterase (PDEIII ) inhibitor (IC₅₀ = 0.45 and 1.0 µM for PDEIIIA and PDEIIIB, respectively). It inhibits other PDE isoforms at much higher...

Minocycline is a broad-spectrum, brain-permeable, tetracycline antibiotic that displays neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. Acts as a matrix metalloproteinase...

MIP-1 alpha human Elisa Kit | K4784

MIP-1 beta human Elisa Kit | K4785

5246 | MIP-1-alpha Antibody DataSheet

5249 | MIP-1-beta Antibody DataSheet

Both MIP-1 and MIP-1 are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the...

MIP-1 is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1 signals through the CCR1 receptor. MIP-1 chemoattracts neutrophils and also...

Human microphage inflammatory protein-1 (MIP-1 is a 7.8 kDa protein containing 70 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue...

Murine macrophage inflammatory protein-1 (MIP-1) is an 7.8 kDa protein containing 69 amino acid residues. It is part of the CC chemokine family and plays an important role in the inflammatory...

Rat macrophage inflammatory protein-1 (MIP-1) is an 8.0 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue...

Human macrophage inflammatory protein-1 (MIP-1 ) is a 7.6 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue...

Murine macrophage inflammatory protein-1 (MIP-1) is a 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue...

MIP-2 Antibody | 5251

vMIP-2 is a chemokine analog encoded by human herpes virus, and has been shown to have antagonist activity towards several chemokine receptors. Recombinant vMIP-2 is a 7.9 kDa protein consisting of...

Murine microphage inflammatory protein-2 (MIP-2) promotes neutrophil chemotaxis and degranulation. ’s murine MIP-2 is a 7.8 kDa protein containing 73 amino acid residues including the ‘RLR’ motif...

MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally,...

Human macrophage inflammatory protein-3 (MIP-3 , Exodus, LARC) is a member of the -chemokine (C-C) family of cytokines. Recombinant human MIP-3 is a 8.0 kDa protein containing 70 amino acid...

Murine macrophage inflammatory protein-3 (MIP-3 , Exodus, LARC) is a member of the -chemokine (C-C) family of cytokines. Recombinant murine MIP-3 is a 7.9 kDa protein containing 70 amino acid...

Human macrophage inflammatory protein-3 (MIP-3 , Exodus-3, ELC) is a member of the -chemokine (C-C) family of cytokines. It plays an important role in the inflammatory response of human T cells and...

Murine macrophage inflammatory protein-3 (MIP-3) is a 9.2 kDa protein containing 83 amino acid residues. It is a chemoattractant for T and B lymphocytes and myeloid progenitor cells.4495 | MIP-3beta...

Human microphage inflammatory protein-4 (MIP-4) also known as PARC, has been shown to be chemotactic for T lymphocytes but not for monocytes or granulocytes. ’s human MIP-4 is an 7.8 kDa protein...

Human macrophage inflammatory protein-5 (MIP-5) also known as Lkn-1 has been shown to be chemotactic for T-lymphocytes but not for monocytes or granulocytes. Recombinant human MIP-5 is a 10.1 kDa...

Miracloth Substitute is an autoclavable, quick filtration material for gelatinous homogenates that is composed of rayon-polyester with an acrylic binder.9248 | Miracloth Substitute DataSheetSort...

Miransertib is an allosteric, pan-Akt inhibitor (IC₅₀s = 5.0, 4.5, and 16 nM for Akt1, Akt2, and Akt3, respectively). It is selective for Akt isoforms over a panel of 303 other kinases. It binds to...

Mirin is a small-molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Mirin blocks the 3' and 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double...

’s miRNA Inhibitor Neg Control is designed to use as a negative control in miRNA inhibitor experiments. It is a random sequence that has been tested and validated to have no effects on miRNA function...

offers miRNA inhibitors, which are chemically-modified and optimized nucleic acids designed to specifically target the microRNA (miRNA) molecules in cells. Endogenous microRNAs are small, regulatory...

Mithramycin A is a DNA-binding, anti-tumor and neuroprotective antibiotic used as a chemotherapeutic agent. It mediates its protective function, in part, by regulating acetylation of histones or...

Mitiglinide calcium is a highly selective potassium channel blocker that stimulates insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide is a...

Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties. Mitochondrial targeting of superoxide scavenging using mito-TEMPO...

Mitochondria Storage Buffer for the storage of intact mitochondria for functional studies.M1104 | Mitochondria Storage Buffer DataSheetSort Name: Mitochondria Storage BufferLabel Name: Mitochondria...

K256 | Mitochondria/Cytosol Fractionation Kit DataSheet

K250 | Mitochondrial Apoptosis Detection Fluorometric Kit MitoCapture DataSheet

Mitochondrial ATP synthase Activity Assay Kit (Colorimetric) | K2112-100Description: Mitochondrial ATP synthase (EC 3.6.3.14), also known as mitochondrial complex V or F1F0-ATP synthase is a...

K968 | Mitochondrial Complex I Activity Colorimetric Assay Kit DataSheet

K520 | Mitochondrial Complex III Activity Assay Kit DataSheet

K280 | Mitochondrial DNA Isolation Kit DataSheet

K389 | Mitochondrial DNA Purification Kit DataSheet

K239 | Mitochondrial Permeability Transition Pore Assay Kit DataSheet

K285 | Mitochondrial Protein IP Kit DataSheet

3882 | Mitofusin 2 Antibody DataSheet

3882BP | Mitofusin 2 Blocking Peptide DataSheetAntibody Target: Mitofusin 2 Accession #: EAW71727Gene ID: 9927Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Mitomycin C is an antitumor antibiotic isolated from Streptomyces sp. Mitomycin is activated by reduction in vivo generating oxygen radicals which produce crosslinks in DNA by alkylaion. This...

Mitoquinone is a mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects. Displays beneficial effects in mouse models of Alzheimer's disease. Mitoquinone protects pancreatic...