26

PACAP (1-38) is an adenylate cyclase activator. More potent than vasoactive intestinal peptide (VIP).PACAP (1-38) is an adenylate cyclase activator. More potent than vasoactive intestinal peptide...

An Antitumor and antileukemic agent. Promotes assembly of microtubules and inhibits tubulin disassemblyPaclitaxel is an antitumor and antileukemic agent. Promotes assembly of microtubules and...

K765 | PAF Acetylhydrolase Activity Assay Kit Colorimetric DataSheet

K766 | PAF Acetylhydrolase PAF-AH Inhibitor Screening Kit Colorimetric DataSheet

6831 | Paf1 polyclonal antibody DataSheet

K860 | PAH p-Aminohippuric Acid Colorimetric Assay Kit DataSheet

5579 | PAI-1 Antibody DataSheet

3908BP | PAK1 Blocking Peptide DataSheetAntibody Target: PAK1Accession #: Q13153Gene ID: 5058Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

3443 | PAK2 Antibody DataSheet

3443BP | PAK2 Blocking Peptide DataSheetAntibody Target: PAK2 Accession #: AAD40374Gene ID: 5062Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3686BP | PAK3 Blocking Peptide DataSheetAntibody Target: PAK3Accession #: O75914Gene ID: 5063Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate buffered...

3444 | PAK4 Antibody DataSheet

3444BP | PAK4 Blocking Peptide DataSheetAntibody Target: PAK4 Accession #: BAF84528Gene ID: 10298Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

PAK4 is a recently identified member of the p21-activated kinases (PAKs) which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases...

3928 | PAK5/PAK7 Antibody DataSheet

3928BP | PAK5/PAK7 Blocking Peptide DataSheetAntibody Target: PAK5/PAK7 Accession #: BAG53104Gene ID: 57144Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5mg/ml) in...

3927BP | PAK6 Blocking Peptide DataSheetAntibody Target: PAK6 Accession #: AAI50755Gene ID: 214230Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5mg/ml) in phosphate...

The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling...

A synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs. Pam3CSK4 is a potent activator of the proinflammatory transcription factor NF-kB. Activation is...

Pamapimod (R-1503, Ro4402257) is a p38 MAPK inhibitor.Pamapimod (R-1503, Ro4402257) is a p38 MAPK inhibitor.B1700 | Pamapimod DataSheetAlternate Name/Synonyms: Pamapimod; R-1503; R 1503; R1503; Ro...

A bisphosphonate compound that inhibits bone resorption, the natural, ongoing process of bone being destroyed by osteoclasts. Also inhibits farnesyl diphosphate synthase (IC₅₀ = 200 nM).Pamidronate...

A pan-caspase inhibitor. Q-VD(OMe)-OPh is the methyl ester derivative of the pan-caspase inhibitor Q-VD-OPh (Cat. No.1170). Esterification of the aspartic acid should enhance the cell-permeability of...

Panobinostat (LBH589) is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumour cell proliferation in vitro. The IC₅₀ values of HDAC isozymes HDAC1-IP Ac-H4, HDAC8,...

5308 | PANX1 Antibody (NT) DataSheet

A useful fluorogenic substrate for tyrosinase. When assaying in phosphate buffer at pH 7.1, the optimal excitation/emission wavelengths are 340/440 nm.A useful fluorogenic substrate for tyrosinase...

K1440 | Papanicolaou Stain Kit DataSheet

An opium alkaloid that acts as a phosphodiesterase inhibitor (IC₅₀ = 13 μM). It increases cellular cAMP levels and alters cellular function. It has been shown to reduce arterial and cerebral...

Paquinimod is a small molecule quinoline-3-carboxamide derivative that acts as a S100A9 inhibitor. It targets the S100A9 protein and disrupts its binding to the pro-inflammatory receptors, Receptor...

3447 | PAR4 Antibody DataSheet

3447BP | PAR4 Blocking Peptide DataSheetAntibody Target: PAR4 Accession #: EAW97348Gene ID: 5074Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K999 | Paraoxonase 1 PON1 Activity Assay Kit Fluorometric DataSheet

E4519 | PARC CCL18 Human Elisa Kit DataSheet

3260 | PARD3 Antibody DataSheet

3260BP | PARD3 Blocking Peptide DataSheetAntibody Target: PARD3Accession #: A5D6P2Gene ID: 93742Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Parecoxib sodium is an injectable prodrug of valdecoxib, that acts as a potent and selective inhibitor of cyclooxygenase-2 (COX-2). Useful for the short-term treatment of postoperative pain in adults...

A selective and irreversible monoamine oxidase –B (MAO-B) inhibitor. Pargyline is also a mechanism-based inhibitor of LSD1 that effectively inhibits histone demethylation in vivo.Pargyline is a...

Paromomycin Sulfate is an aminoglycoside antibiotic that inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which...

Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI). It has a variety of uses, including the treatment of anxiety...

3000 | PARP Antibody (Clone 10H) DataSheet

A1109 | PARP Antibody (Clone 2B6) DataSheet

3023 | PARP Antibody (Clone 7A10) DataSheet

6659 | PARP Antibody (Clone 839120) DataSheet

3002 | PARP Antibody DataSheet

3140 | PARP (Cleaved) Antibody DataSheet

Poly-ADP-ribose metabolism plays a major role in a wide range of biological processes, such as maintenance of genomic stability, transcriptional regulation, energy metabolism and apoptosis. PARP1...

K4218 | PARP1 Human Elisa Kit DataSheet

An anti-inflammatory agent. Specifically inhibits activation of NF-κB by preventing the degradation of IκBα and IκBβ. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and...

A convenient set consisting of fourteen inhibitors useful for the study of EGFR signaling pathway. The fouteen inhibitors are: 5 mg of AG 490 (Cat. No. 1570-5), 1 mg of Akt Inhibitor,...

A convenient set consisting of eight inhibitors useful for studying JAK/STAT signaling pathway. The inhibitors are: 5 mg of AG 490 (Cat. No. 1570-5), 5 mg of CP-690550 (Cat. No. 1622-5), 500 µg of...

A convenient set consisting of seven inhibitors useful for the study of MAP Kinase signaling pathway. The seven inhibitors are: 1 mg of PD 184352 (Cat. No. 1585-1), 5 mg of PD 98059 (Cat. No...

A convenient set consisting of eleven inhibitors useful for the study of PI3-K/Akt/mTOR pathway. The 11 inhibitors are: 1 mg of Akt Inhibitor, Isozyme-selective (Cat. No. 1708-1), 5 mg of BEZ-235...

3636R | PAX6 Antibody DataSheet

Antibody Target: PAX6 Accession #: EDL79723Gene ID: 25509Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 1%...

3636 | PAX6 Polyclonal Antibody DataSheet

3448 | Paxillin Antibody DataSheet

3044 | PBR Antibody DataSheet

3044BP | PBR Blocking Peptide DataSheetAntibody Target: PBR Accession #: BAA04749Gene ID: 2257Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate buffered...

One of the most commonly used buffers provided in a convenient, tablet form. PBS is isotonic and non-toxic to cells and has the ability to maintain their osmolarity thereby making the buffer suitable...

One of the most commonly used buffers provided in a convenient, tablet form. PBS is isotonic and non-toxic to cells and has the ability to maintain their osmolarity thereby making the buffer suitable...

PBS-Tween buffer contains the non-ionic detergent Tween® 20 which acts through blocking. It has the ability to reduce non-specific binding and protein-protein interaction during the wash step in...

PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. DprE1 is an an essential enzyme involved in the cell wall biosynthesis of Corynebacterineae.PBTZ169 is a...

6763 | PCAF Antibody (CT) DataSheet

6762 | PCAF Antibody (NT) DataSheet

6675 | PCAF Antibody DataSheet

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such...

K345 | pCAF Inhibitor Screening Kit Fluorometric DataSheet

PCAF mouse recombinant | 7556

PCI 34051 is a potent histone deacetylase 8 (HDAC8) inhibitor (IC₅₀ = 0.01 μM) with >200-fold selectivity over HDAC isoforms 1, 2, 3, 6, and 10 (IC₅₀s = 4, >50, >50, 2.9, and 13 μM, respectively)...

PCI-29732 is a selective and irreversible BTK (Bruton’s tyrosine kinase) inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay. Blocks B cell antigen receptor (BCR)-mediated gene...

3350R | PCNA Antibody DataSheet

3350RBP | PCNA Blocking Peptide DataSheetAntibody Target: PCNAAccession #: CAG38740.1Gene ID: 5111Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Expression of proliferating cell nuclear antigen (PCNA) or cyclin or polymerase auxiliary protein is elevated in the nucleus during late G1 phase immediately before the onset of DNA synthesis,...

PCNA (Proliferating Cell Nuclear Antigen) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a...

K1444 | PCR DNA extraction and purification kit DataSheet

K903 | PCR Quick Screening Kit, InsertFinder DataSheet

K1453 | PCR-Campylobacter Detection Kit DataSheet

K1450 | PCR-Legionella spp Detection Kit DataSheet

K1451 | PCR-Legionella spp Plus Detection Kit DataSheet

K1449 | PCR-Listeria monocytogenes Detection Kit DataSheet

K1447 | PCR-Salmonella Detection Kit DataSheet

K1448 | PCR-Salmonella-Listeria Detection Kit DataSheet

K1452 | PCR-STEC Detection Kit DataSheet

pCREB Transcription Factor Activity Assay Kit (Colorimetric) | K2109-100Description: CREB (cAMP response element-binding protein) is a phosphorylation-dependent cellular transcription factor. It is...

K7265 | PCSK9 human Elisa Kit DataSheet

K7266 | PCSK9 mouse Elisa Kit DataSheet

Cell-permeable. A selective, non-competitive Calpain inhibitor (Ki = 210 nM and 370 nM for Calpain-1 and Calpain-2, respectively). Interacts with the calcium-binding domain of calpain.PD 150, 606 is...

An extremely potent and specific inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC₅₀ = 25 pM). Inhibits other purified kinases only at micromolar or higher concentrations.PD...

PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor (IC50 = 89 nM).PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor (IC50 = 89 nM).B1703 | PD...

A potent and selective FGFR1 tyrosine kinase inhibitor (IC₅₀ = 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of...

A potent, selective and cell-permeable inhibitor of MAP kinase kinase (MEK). It inhibits phosphorylation of MAP kinase by MEK. PD 98059 does not inhibit MAP kinase itself.PD 98059 is a potent,...

A selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC₅₀ = 0.33 nM). In combination with the GSK-3 inhibitor CHIR99021, prevents...

PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a panel of 34 additional protein kinases (IC₅₀ values are > 10 μM)...

K4153 | PD-1 human Elisa Kit DataSheet

PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. Also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is...

PD-1/PD-L1 Inhibitor 2 is a novel immunomodulator that prevents the interaction of PD-L1 with PD-1 (IC₅₀ = 18 nM).PD-1/PD-L1 Inhibitor 2 is a novel immunomodulator that prevents the interaction of...

Programmed death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the...

PD-123319 is a potent, selective, non-peptide angiotensin AT2 receptor antagonist (IC₅₀ values are 34 and 210 nM in rat adrenal tissue and brain respectively). It has been used to selectively examine...

A specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (Ki = 197nM). Displays only weak effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC₅₀ = 0.54 μM for 15-LOX in rabbit reticulocytes).PD-146176 is...

PD-166285 is a potent, ATP-competitive and broadly active protein tyrosine kinase inhibitor. It inhibits tyrosine kinases c-Src, fibroblast growth factor receptor 1 (FGFR1), and platelet-derived...

PD-166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) (IC₅₀ = 55 nM). It has no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4...