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Nek7 is a member of the NIMA (never in mitosis, gene A) family of serine/threonine kinases. In contrast to the other documented NIMA-related kinases, Nek7 harbor its catalytic domain in the...

E4611 | Neomycin Elisa Kit DataSheet

Neomycin sulfate is a broad spectrum aminoglycoside antibiotic composed of a number of related neomycin compounds including neomycin A (neamine), neomycin B (framycetin), neomycin C, and a few minor...

Neoseptin-3 is a Toll-like receptor 4/myeloid differentiation factor 2 (mTLR4/MD-2) agonist (EC50 of 18.5 μM). Neoseptin-3 stimulates the activity of mouse TLR4 (mTLR4)/myeloid differentiation factor...

A1150 | Nephrin Antibody DataSheet

K487 | Neprilysin Activity Assay Kit Fluorometric DataSheet

K996 | Neprilysin Inhibitor Screening Kit Fluorometric DataSheet

Cell-permeable. A second-generation inhibitor of the ErbB family of receptor kinases. Neratinib acts as an irreversible inhibitor of the epidermal growth factor receptor (EGFR) and human epidermal...

Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Originally identified as a hypothalamic neuropeptide, Nesfatin-1 is also...

Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the...

Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the...

3208 | Nestin Antibody DataSheet

K4191 | Nestin Human Elisa Kit DataSheet

Netarsudil Hydrochloride (AR-13324) is a Rho kinase (ROCK) inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous humor. Netarsudil (AR-13324) is a potent,...

Netilimicin is an aminoglycoside antibiotic. It is active against S. aureus, N. gonorrhoeae, E. coli, P. mirabilis, and P. aeruginosa (MIC values = 0.4, 3.1, 0.8, 1.6, and 0.4 µg/ml, respectively) as...

Immunoplates for Exosome capture and quantification from human biofluids (plasma, serum, urine, saliva) and from human or mouse cell media. Transparent, white and black plates are available depending...

NeuralExoPure™ Immunoplates (Exosome Isolation, plasma, fluorimetric assay) | M1021

NeuralExoPure™ Immunoplates (Exosome Isolation, plasma, luminometric assay) | M1020

K732 | Neuraminidase Activity Fluorometric Assay Kit DataSheet

K4711 | Neuregulin-1/NRG1-beta1 human Elisa Kit DataSheet

Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and...

6650 | Neuregulin/Heregulin-1? Antibody DataSheet

3428 | Neurexin Antibody DataSheet

3428BP | Neurexin Blocking Peptide DataSheetAntibody Target: Neurexin Accession #: Q9Z2A0Gene ID: 116508Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in post...

Cell-permeable. A promoter of neurogenesis. Neurodazine induces neuronal differentiation in skeletal muscle cells. In mouse C2C12 myoblasts, neurodazine (2 μM for seven days) upregulated the...

A convenient set of three small molecule modulators for enhancing neuronal transdifferentiation. The three products are: SB-431542 (Cat. No. 1674-1), LDN193189 (Cat. No. 1995-1) and CHIR99021 (Cat...

A convenient set of two small molecule modulators for enhancing neuronal transdifferentiation. The two products are: SB-431542 (Cat. No. 1674-1) and CHIR99021 (Cat. No. 1677-1).Neuronal...

A convenient set of four small molecule modulators for enhancing neuronal transdifferentiation. The four products are: SB-431542 (Cat. No. 1674-1), LDN193189 (Cat. No. 1995-1), CHIR99021 (Cat. No...

A convenient set of four small molecule modulators for enhancing neuronal transdifferentiation. The four products are: SB-431542 (Cat. No. 1674-1), LDN193189 (Cat. No. 1995-1), CHIR99021 (Cat. No...

Cell-permeable. Selectively induces neuronal differentiation of primary hippocampal neural progenitor cells. It is more potent and selective compared to retinoic acid. Also suppresses astrocyte...

3856 | Neuropilin-1 Antibody DataSheet

3856BP | Neuropilin-1 Blocking Peptide DataSheetAntibody Target: Neuropilin-1 Accession #: AAH60129Gene ID: 18186Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1),...

Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it...

K447 | Neutral Red Cell Cytotoxicity Assay Kit DataSheet

K383 | Neutrophil Elastase Activity Assay kit Fluorometric DataSheet

K782 | Neutrophil Elastase Inhibitor Screening Kit Fluorometric DataSheet

Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5.02 ± 0.60 nM). Displays 600-, 1380-, 1330-, 1870-, -2330,...

NF-kB p65 Human Transcription Factor Activity Assay Kit | E4330

This peptide contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-κB p50 linked to a peptide cell-permeablization sequence, the hydrophobic region...

3038BP | NFkB Blocking Peptide DataSheetAntibody Target: NFkB Accession #: NP_033071Gene ID: 19697Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3897 | NFkB p105 Antibody DataSheet

3897BP | NFkB p105 Blocking Peptide DataSheetAntibody Target: NFkB p105Accession #: BAF84139Gene ID: 4790Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3354R | NFkB p50 Antibody DataSheet

3354RBP | NFkB p50 Blocking Peptide DataSheetAntibody Target: NFkB p50 Accession #: BAF84139.1Gene ID: 4790Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3354 | NFkB p50 Polyclonal Antibody DataSheet

NFkB p65 Antibody Clone 2A12A7 | 3012

3038 | NFkB p65 Antibody DataSheet

K4202 | NFKB1 Human Elisa Kit DataSheet

NFNB, also known as NFSB, shows the ability to reduce quinines. This protein is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. It also capable of reducing...

NG 52 (Compound 52 ) is a potent, selective, cell-permeable, and reversible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC₅₀ = 7 μM), and the related Pho85p kinase (IC₅₀ = 2 μM).NG 52...

Nerve growth factor- (NGF-) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NGF- is a dimer, formed by two identical...

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NGF-β is a dimer, formed by two...

Nerve growth factor- (NGF-) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active recombinant mouse NGF- is a homodimer, non-glycosylated...

6789 | NGFR Antibody (Clone # 8G3G10) DataSheet

5307 | NGN2 Antibody (CT) DataSheet

NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria. It inhibits histidine protein kinase YycG with an IC₅₀ of 6.6 µM. It selectively inhibits eEF-2 kinase...

3521 | NHERF1/ EBP50 Antibody DataSheet

Antibody Target: NHERF1/ EBP50 Accession #: Q9JJ19Gene ID: 59114Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2,...

NI-57 is an inhibitor of the bromodomains of BRPF proteins. The bromodomain and plant homeodomain finger-containing (BRPF) family are scaffolding proteins important for the recruitment and activation...

Protein activity and functional studies rely largely on the availability of purified target proteins. Majority of protein studies are carried out on tagged recombinant proteins expressed in various...

NIAD-4 is a novel class of fluorescent probe, having good blood-brain barrier permeability, specificity to amyloid-β plaques, and "turn-on" bright far-red emission upon Aβ binding. NIAD-4 has a...

K510 | Nickel Colorimetric Assay Kit DataSheet

A STAT3 signaling pathway inhibitor. Niclosamide potently inhibits the activation and transcriptional function of STAT3 and induces cell growth inhibition, apoptosis, and cell cycle arrest of cancer...

N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. NNMT is an important cytosolic methyltransferase catalyzing the N-methylation of nicotinamide,...

Nidufexor is an agonist of Farnesoid X receptor (FXR). Administration of Nidufexor (10 and 30 mg/kg for 3 weeks) modulates FXR-dependent genes in vivo leading to the reduction of steatosis,...

3737 | NIF1 Antibody DataSheet

3737RBP | NIF1 Blocking Peptide DataSheetAntibody Target: NIF1 Accession #: BAG59529Gene ID: 63925Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Nigericin is a polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K⁺> Rb⁺ Cs⁺>> Na⁺. Also activates NLRP3/NALP3 and signals...

3193 | NIK Antibody DataSheet

3193RBP | NIK Blocking Peptide DataSheetAntibody Target: NIK Accession #: Gene ID: Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered saline...

A potent, selective BCR-ABL inhibitor that fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib (Cat. No. 1625-100, 1000). Nilotinib is not only more potent than...

A terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and anticancer activity. Recently it has also been shown that...

Nimesulide is a selective cyclooxygenase-2 (COX-2) inhibitor. The IC₅₀ values are 70 and 1.27 µM for human recombinant COX-1 and -2 (at 20 µM arachidonic acid), respectively, and 22 and 0.03 µM for...

Nimorazole is a 5-nitroimidazole derivative that displays antimicrobial activity. Used in the treatment of intestinal protozoal infections. Also acts as a hypoxic radiosensitizer.Nimorazole is a...

Nimustine is a nitrosourea compound that displays anticancer activity. Nimustine induces DNA cross-linking and double-stranded DNA breaks. Nimustine is clinically used to treat gliomas and may also...

Nitazoxanide is a nitrothiazole benzamide with anti-parasitic and anti-viral activity. It inhibits pyruvate-ferredoxin oxidoreductase in protozoa and anaerobic bacteria. It inhibits many anerobes in...

K979 | Nitric Oxide Cell-Based HTS Assay Kit DataSheet

K262 | Nitric Oxide Colorimetric Assay Kit DataSheet

K252 | Nitric Oxide Fluorometric Assay Kit DataSheet

K205 | Nitric Oxide Synthase NOS Activity Assay Kit Colorimetric DataSheet

K206 | Nitric Oxide Synthase NOS Activity Assay Kit Fluorometric DataSheet

K208 | Nitric Oxide Synthase NOS Inhibitor Screening Kit Fluorometric DataSheet

K544 | Nitrite Assay Kit Griess Reagent DataSheet

Nitrocefin is the chromogenic cephalosporin that acts as an excellent β-lactamase substrate. It exhibits a rapid distinctive color change from yellow (max at pH 7.0 = 390 nm) to red (max at pH 7.0 =...

E4275 | Nitrofurantoin AHD Elisa Kit DataSheet

Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit...

5413 | Nitrotyrosine Antibody (7A5) DataSheet

5414 | Nitrotyrosine Antibody (HM11) DataSheet

5415 | Nitrotyrosine Antibody (NOY-7A5) DataSheet

5416 | Nitrotyrosine Antibody DataSheet

NKH477 is a water-soluble analog of the adenylyl cyclase activator Forskolin (Cat. No. 1531). Like forskolin, NKH477 activates adenylyl cyclases without altering the activity of phosphodiesterases or...

NKL 22 (also known as MDK-4154) is a cell-permeable compound that acts as a FXN- (frataxin gene) specific HDAC (histone deacetylase) inhibitor. It reverses the silencing of FXN transcription in FRDA...

NLG919 is a potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway (Ki = 7 nM). Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by...

NLRP3i is an intermediate in the glyburide synthesis that acts as a NLRP3 inflammasome inhibitor. It inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size...

Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their levels have been...

NME2, also known as NM23B, is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme,...

NME3, also known as, a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. It is important for the...

NME4 human recombinant | 7826