Oct3/4 Antibody| F41526-0.08ML/F41526-0.4ML

Oct3/4 Antibody| F41526-0.08ML/F41526-0.4ML | Gentaur UK, US & Europe Distribution

Background: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:50-1:100

Application Note: Titration of the Oct3/4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Oct3/4 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 265-297 from the human protein was used as the immunogen for this Oct3/4 antibody.

Storage: Aliquot the Oct3/4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A