WNT3 Antibody| F43549-0.08ML/F43549-0.4ML/F54041-0.1ML/R33241-100UG

WNT3 Antibody| F43549-0.08ML/F43549-0.4ML/F54041-0.1ML/R33241-100UG | Gentaur UK, US & Europe Distribution

Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Chicken, Xenopus

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the WNT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This WNT3 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 155-184 from the human protein was used as the immunogen for this WNT3 antibody.

Storage: Aliquot the WNT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A