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A potent and selective pan-TRK inhibitor, suppressing the activity of TrkA and TrkB with IC50 of 8 and 12 nM, respectivelyA potent and selective pan-TRK inhibitor, suppressing the activity of TrkA...

GNF-7 is a multi-targeted kinase inhibitor that inhibits activated CDC42 kinase 1 (ACK1) and germinal center kinase (GCK) inducing cell cycle arrest and apoptosis in leukemia cells harboring NRAS...

GnRH ELISA Kit | E5099-100Description: Gonadotropin-releasing hormone (GnRH) is produced and secreted by specialized nerve cells in the hypothalamus of the brain. It is released into tiny blood...

Cell-permeable. A potent protein kinase C (PKC) inhibitor (IC₅₀ = 7.9 nM). In vitro, discriminates between Ca²⁺-dependent and -independent isoforms of PKC; selectively inhibits PKCα and PKCβ1 (IC₅₀...

Gö 6983 is a broad-spectrum Protein Kinase C (PKC) inhibitor; inhibits several isoforms of protein kinase C with IC₅₀ values of 7, 7, 6, 10, 60, and 20,000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ, and...

6915 | Goat Anti-Human IgG (H&L) FITC DataSheet

6916 | Goat Anti-Human IgG (H&L) HRP DataSheet

6902 | Goat Anti-Mouse IgG (H&L) AMCA DataSheet

6917 | Goat Anti-Mouse IgG (H&L) AP DataSheet

6918 | Goat Anti-Mouse IgG (H&L) Biotin DataSheet

6900 | Goat Anti-Mouse IgG (H&L) Cy3 DataSheet

6919 | Goat Anti-Mouse IgG (H&L) FITC DataSheet

6920 | Goat Anti-Mouse IgG (H&L) HRP DataSheet

6901 | Goat Anti-Mouse IgG (H&L) Texas Red DataSheet

6921 | Goat Anti-Mouse IgG (H&L) TRITC DataSheet

6922 | Goat Anti-Mouse IgG (H&L) Unconjugated DataSheet

6905 | Goat Anti-Rabbit IgG (H&L) AMCA DataSheet

6923 | Goat Anti-Rabbit IgG (H&L) AP DataSheet

6924 | Goat Anti-Rabbit IgG (H&L) Biotin DataSheet

6903 | Goat Anti-Rabbit IgG (H&L) Cy3 DataSheet

6925 | Goat Anti-Rabbit IgG (H&L) FITC DataSheet

Goat Anti-Rabbit IgG (H&L) TRITC

6927 | Goat Anti-Rabbit IgG (H&L) Unconjugated DataSheet

6910 | Goat Anti-Rat IgG (H&L) Biotin DataSheet

6906 | Goat Anti-Rat IgG (H&L) Cy3 DataSheet

6907 | Goat Anti-Rat IgG (H&L) FITC DataSheet

6908 | Goat Anti-Rat IgG (H&L) HRP DataSheet

6909 | Goat Anti-Rat IgG (H&L) TRITC DataSheet

The purified total goat IgG can be used as a negative control for antibodies in Western blot, immunoprecipitation, and immunohistochemistry, etc.M1102 | Goat IgG DataSheetSort Name: Goat IgGLabel...

ADP-ribosylation factor 1 (Arf1) plays an important role in regulating secretory traffic and membrane transport within the Golgi. Arf1 is activated by guanine nucleotide exchange factors (ArfGEFs)...

Golvatinib ( E7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with...

A glucoside occurring in cotton and Hubiscus flowers that acts as a potent antimelanoma agent. Gossypin inhibits human melanoma cell proliferation, in vitro, in melanoma cell lines that harbors both...

Glutamic-oxaloacetic transaminase (GOT) is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid...

GOT2, also known as glutamate oxaloacetate transaminase 2, belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Glutamate oxaloacetate transaminase is a pyridoxal...

Glucose-6-phosphate isomerase, also known as GPI, belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by...

GPNA is a substrate for γ-glutamyl transpeptidase. GPNA has also been shown to be an inhibitor of glutamine uptake - solute-linked carrier family A1 member 5 (SLC1A5). Cellular uptake of L-glutamine...

5215 | GPR15 Polyclonal Antibody DataSheet

GPT, also known as alanine aminotransferases (ALT1), catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. This protein plays a key role in the...

Alanine aminotransferase 2, also known as GPT2, catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Subsequently, they play a key role in the...

3818BP | GPV1 Blocking Peptide DataSheetAntibody Target: GPV1Accession #: Q9HCN6Gene ID: 51206Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

3818 | GPVI Antibody DataSheet

k1428 | Gram Stain Kit DataSheet

Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from Bacillus brevis. Gramicidin A is a linear channel-forming ionophore pentadecapeptide that forms a...

Gramicidin is a Linear polypeptide antibiotic complex, a mixture of gramicidin A, B, C, and D. Gramicidin D, a channel-forming ionophore, which are active against most Gram-positive bacilli and...

Granisetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 3.9 nM) with antiemetic activity. It displays selectivity for 5-HT3 over 5-HT4 receptors (Ki = >1,000 nM)...

Granzyme A is a member of the granzyme family. Granzyme A is the most abundant serine protease in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A has a specific function in...

K168 | Granzyme B Activity Fluorometric Assay Kit DataSheet

3073 | Granzyme B Antibody (Clone B18.1) DataSheet

6683 | Granzyme B Antibody DataSheet

3073RBP | Granzyme B Blocking Peptide DataSheetAntibody Target: Granzyme B Accession #: NP_004122Gene ID: 3002Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 μg (0.5 mg/ml) in...

K4279 | Granzyme B human Elisa Kit DataSheet

A synthetic peptide that inhibits Granzyme B.Ac-IEPD-CHO is a synthetic peptide-based, reversible inhibitor of Granzyme B.1119 | Granzyme B Inhibitor Ac-IEPD-CHO DataSheetAlternate Name/Synonyms:...

K169 | Granzyme B Inhibitor Screening Kit Fluorometric DataSheet

A synthetic peptide that irreversibly inhibits granzyme B activity. The inhibitor is designed as a methyl ester to facilitate cell permeability.Z-AAD-CMK is a irreversible Granzyme B inhbitor.1128 |...

3173 | Granzyme B Monoclonal Antibody DataSheet

Granzyme B (GZMB) is a serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin,...

Granzyme B (GZMB) is a serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and enters the target cell,...

Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV)...

3992 | Green Fluorescence Protein (GFP) Antibody (Clone BV-F4) DataSheet

Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mos-transformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding...

Gremlin-1 (isoform-1) belongs to a group of diffusible proteins which bind to ligands of the TGF- family and regulate their activity by inhibiting their access to signaling receptors. The interplay...

5657 | Gremlin-2 Antibody DataSheet

3492 | GRIM-19 Polyclonal Antibody DataSheet

G protein-coupled receptor kinases (GRKs) play an important role in phosphorylating and regulating the activity of a variety of G protein-coupled receptors. Haribabu and Snyderman (1) identified GRK5...

GRL-0617 is a potent inhibitor of the papain-like protease (PLpro) from the coronavirus that causes severe acute respiratory syndrome (SARS-CoV). PLpro cleaves the viral polyproteins. GRL-0617...

Human GRO/MGSA (also known as GRO ) promotes neutrophil chemotaxis and degranulation. It also stimulates mutagenesis in certain human melanoma cells. Recombinant human GRO/MGSA is a 7.8 kDa protein...

Human GRO- is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. GRO- like GRO- specifically inhibits growth factor-stimulated proliferation...

Rat GRO-beta/MIP-2 promotes neutrophil chemotaxis and degranulation. Recombinant rat GRO-beta is a 7.9 kDa protein containing 73 amino acid residues.4108 | GRO-beta/MIP-2 rat recombinant...

Human GRO- is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. Recombinant human GRO- is a 7.9 kDa protein containing 73 amino acid...

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7...

Murine KC (also known as murine GRO-) belongs to the C-X-C family of chemokines. ’s murine KC is a 7.8 kDa protein containing 72 amino acid residues.4210 | GRO/KC murine recombinant...

A convenient set containing three recombinant human growth factors including recombinant human Flt3-Ligand, Stem Cell Factor (SCF), and Thrombopoietin (TPO) that are commonly used for Stem Cell...

A convenient set containing three recombinant human growth factors including Granulocyte Colony Stimulating Factor (G-CSF), Stem Cell Factor (SCF), and Thrombopoietin (TPO) that are commonly used for...

A convenient set containing three recombinant human growth factors including Bone Morphogenetic Protein-2 (BMP-2), Fibroblast Growth Factor-2 (FGF-2), and Insulin- like Growth Factor I (IGF-I), that...

Growth Factor Set IV StemBoost | K426

A convenient set containing five recombinant human growth factors including Erythropoietin- α (EPO-α), Granulocyte Macrophage Colony Stimulating Factor (GM-CSF), Interleukin-3 (IL-3), Interleukin-6...

K7412 | Growth Hormone human Elisa Kit DataSheet

GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus...

GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus...

Recombinant Human Pituitary Growth Hormone produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 192 amino acids and having a molecular mass of 22367 Dalton. Pituitary Growth...

GH is a member of the somatotropin/prolactin family of hormone which plays an important role in growth control. Recombinant mouse Growth Hormone produced in E.Coli is a single, non-glycosylated,...

GS-441524 is the predominant metabolite of remdesivir in blood and is the nucleoside of the prodrug remdesivir. It is phosphorylated to the active triphosphate metabolite which incorporates into RNA...

GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).2669 |...

GSA 10 is a novel, potent activator of the smoothened receptor (Smo). GSA 10 acts at Smo and promotes the differentiation of multipotent mesenchymal progenitor cells into osteoblasts (EC₅₀ = 1.2 µM)...

3308 | GSAP Antibody DataSheet

3308BP | GSAP Blocking Peptide DataSheetAntibody Target: GSAPAccession #: A4D1B5Gene ID: 54103Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

GSK1016790A is a transient receptor potential vanilloid 4 (TRPV4) agonist that elicits calcium influx in HEK cells expressing mouse or human transient TRPV4 with EC₅₀ values of 18 and 2.1 nM,...

GSK’872 is a potent, selective, and reversible RIPK3 (receptor-interacting protein kinase-3) inhibitor.GSK’872 is a potent, selective, and reversible RIPK3 (receptor-interacting protein kinase-3)...

GSK-046 (iBET-BD2) is a potent and selective inhibitor of BET (bromodomain and extraterminal domain) with IC50 of 264 nM, 98 nM, 49 nM and 214 nM for BRD2BD2, BRD3BD2, BRD4BD2 and BRDTBD2,...

GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively).GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥...

GSK-1059615 is a potent, reversible, ATP-competitive inhibitor of PI3Kα (IC₅₀ = 2 nM). It inhibits proliferation in BT474 cells and attenuates MAPK signaling.GSK-1059615 is a potent, reversible,...

GSK-106 is a useful negative control for PAD4 inhibitors (GSK-121 and GSK-484). It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil...

GSK-1070916 is a potent, reversible and ATP-competitive inhibitor of Aurora kinases B and C with IC₅₀ value of 3.5 nM and 6.5 nM, respectively. Treatment of GSK-1070916 suppresses cell proliferation...

A potent and selective allosteric inhibitor of the MEK1 (IC₅₀ = 0.7 nM) and MEK2 (IC₅₀ = 0.9 nM) enzymes with potential antineoplastic activity.GSK-1120212 is a potent and selective allosteric...

GSK-121 is a novel protein arginine deiminase 4 (PAD4) inhibitor. GSK-121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC₅₀ value of 3.2 µM.GSK-121 is...

GSK-1292263 is a novel GPR119 receptor agonist and is used for the treatment of type 2 diabetes. GSK1292263 improves glucose regulation in animal models of diabetes, but has no effect on plasma...

GSK-1838705A is a potent small-molecule kinase inhibitor that inhibits IGF-IR and IR (insulin receptor) with IC₅₀s of 2.0 and 1.6 nM, respectively. It also inhibits anaplastic lymphoma kinase (ALK)...

GSK-1940029 is a potent stearoyl-coA desaturase (SCD) inhibitorGSK-1940029 is a potent stearoyl-coA desaturase (SCD) inhibitorB2373 | GSK-1940029 DataSheetAlternate Name/Synonyms:...

GSK-199 is a potent, reversible inhibitor of PAD4 (IC₅₀ = 200 nM. It binds to the low-calcium form of the enzyme and is selective for PAD4 over PAD1-3. It is less potent than the related PAD4...

GSK-2018682 is a potent sphingosine -1 phosphate receptor (S1PR)-1 agonist; useful for the treatment of multiple sclerosis. GSK-2018682 induces acute, transient and non-symptomatic decreases in heart...