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A potent (1000-fold) peroxisome proliferator-activated receptor (PPAR)γ agonist. Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.GW1929 is a potent...

A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits...

A selective agonist for PPARδ (peroxisome proliferator-activated receptorδ) (EC₅₀ = 1. 1 nM), displaying 1000-fold selectivity over the other human subtypes. In macrophages, fibroblasts, and...

GW788388 is a potent and selective inhibitor of transforming growth factor beta receptor I (TGF-βR1) (activin receptor-like kinase 5, ALK5) (IC₅₀ = 18 nM). Also inhibits TGF-β type II receptor and...

A slow-releasing, water-soluble hydrogen sulfide (H₂S) donor. Displays vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive)...

GZD824 is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC₅₀ of 0.34 nM and 0.68 nM, respectively.GZD824 is a novel orally bioavailable Bcr-Abl inhibitor for...

H-7 is a Protein kinase inhibitor that inhibits the activity of PKA, PKC, PKG and MLCK with IC₅₀ values of 3.0, 6.0, 5.8 and 97.0 µM, respectively.H-7 is a Protein kinase inhibitor that inhibits the...

A cell-permeable, ATP-competitive inhibitor of Protein Kinase A (PKA) (IC₅₀ = 50 nM). Also inhibits other kinases, including MSK1 , S6K1 and ROCKII with IC₅₀ values of 120 nM, 80 nM and 270 nM...

6823 | H2Apan polyclonal antibody DataSheet

6824 | H2Bpan polyclonal antibody DataSheet

6806 | H3 Pan Antibody DataSheet

H3B-6527 is an orally bioavailable inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity.H3B-6527 is an orally bioavailable inhibitor of human...

6867 | H3K18ac polyclonal antibody DataSheet

6868 | H3K23ac polyclonal antibody DataSheet

6869 | H3K27ac polyclonal antibody DataSheet

6815 | H3K27me1 polyclonal antibody DataSheet

6816 | H3K27me2 polyclonal antibody DataSheet

6870 | H3K27me3 polyclonal antibody DataSheet

6810 | H3K27me3S28p polyclonal antibody DataSheet

6817 | H3K36me1 polyclonal antibody DataSheet

6805 | H3K36me2 Antibody DataSheet

6818 | H3K4ac polyclonal antibody DataSheet

6864 | H3K4me1 polyclonal antibody DataSheet

6865 | H3K4me2 polyclonal antibody DataSheet

6866 | H3K4me3 polyclonal antibody DataSheet

6811 | H3K79me1 polyclonal antibody DataSheet

6812 | H3K79me2 polyclonal antibody DataSheet

6813 | H3K79me3 polyclonal antibody DataSheet

6871 | H3K9/14ac polyclonal antibody DataSheet

6872 | H3K9ac polyclonal antibody DataSheet

6809 | H3K9acS10p Antibody DataSheet

6804 | H3K9me1 Antibody DataSheet

6814 | H3K9me2 polyclonal antibody DataSheet

6873 | H3K9me3 polyclonal antibody DataSheet

6808 | H3K9me3S10p Antibody DataSheet

6803 | H3R17me2 Antibody DataSheet

6875 | H3R17me2(asym)K18ac polyclonal antibody DataSheet

6874 | H3R17me2 polyclonal antibody DataSheet

6876 | H3S10p polyclonal antibody DataSheet

6819 | H4K20me1 monoclonal antibody DataSheet

6877 | H4K20me3 polyclonal antibody DataSheet

6822 | H4K5,8,12,16ac polyclonal antibody DataSheet

6821 | H4K5,8,12ac polyclonal antibody DataSheet

6820 | H4K5ac polyclonal antibody DataSheet

6807 | H4K8ac Antibody DataSheet

6878 | H4K8ac polyclonal antibody DataSheet

6825 | H4pan polyclonal antibody DataSheet

HA 130 is a potent and eversible inhibitor of autotaxin (ATX) (IC₅₀ = 28 nM). It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma...

3924 | HA (Influenza A Virus Hemagglutinin) Antibody DataSheet

3996 | HA-Tag Antibody (Clone 12CA5[2]) DataSheet

HA14-1 is a potent, cell-permeable Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human cancer cells. Also binds to the antiapoptotic Blc-2 proteins Bcl-XL...

3264 | HADH/HCDH Antibody DataSheet

3264BP | HADH/HCDH Blocking Peptide DataSheetAntibody Target: HADH/HCDH Accession #: Q9WVK7Gene ID: 113965Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

HAGH is a member of the glyoxalase family and a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. This protein is a detoxifying enzyme of glycolysis byproduct...

Halofuginone is an an ATP-dependent inhibitor prolyl-tRNA synthetase (Ki of 18.3 nM). Halofuginone attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Blocks expression of MMP2 and...

7017 | Haptoglobin Polyclonal Antibody DataSheet

Of the three haptoglobin phenotypes, Hp 1-1 is the most effective in binding free hemoglobin and in suppressing the inflammatory responses associated with free hemoglobin. Hp 1-1 protects against...

Haptoglobin 2-2 (Hp 2-2) is the least effective of the three haptoglobin phenotypes in binding free hemoglobin and therefore provides less antioxidant benefits than Hp 1-1. Hp 2-2 is associated with...

An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three...

Harmine is a potent and specific inhibitor of both the kinase activity and autophosphorylation of tyrosine during translation DYRK1A (IC₅₀’s: DYRKA1A = 33 nM; DYRKA1B = 166 nM; DYRK2 = 1.9 µM; DYRK4...

Harzianum A is a trichothecene fungal metabolite isolated from T. harzianum. It is cytotoxic to HeLa, MCF-7, and HT-1080 cells (IC50s = 5.07, 10.13, and 0.65 μg/ml, respectively) and displays...

A potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.HAT Activator, CTPB is a potent activator of p300 HAT (histone...

K332 | HAT Activity Colorimetric Assay Kit DataSheet

K334 | HAT Activity Fluorometric Assay Kit DataSheet

K336 | HAT H4 Activity Fluorometric Assay Kit DataSheet

3689 | HAT-1 Antibody DataSheet

3689BP | HAT-1 Blocking Peptide DataSheetAntibody Target: HAT-1 Accession #: NP_115564Gene ID: 84148Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3692 | HAT-2 Antibody DataSheet

3692BP | HAT-2 Blocking Peptide DataSheetAntibody Target: HAT-2 Accession #: AAH32640Gene ID: 11143Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3707 | HAT-3 Antibody DataSheet

3707BP | HAT-3 Blocking Peptide DataSheetAntibody Target: HAT-3Accession #: NP_006757Gene ID: 7994Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

K4258 | HB-EGF Human Elisa Kit DataSheet

HB-EGF is an EGF related growth factor which signals via the EGF receptor, and stimulates the proliferation of SMC (smooth muscle cells), fibroblasts, epithelial cells and keratinocytes. HB-EGF is...

HB-EGF is an EGF related growth factor which signals via the EGF receptor, and stimulates the proliferation of SMC (smooth muscle cells), fibroblasts, epithelial cells and keratinocytes. HB-EGF is...

Hepatitis B virus is a member of the Hepadnavirus family. Virion diameter of this virus is 22 nm. Lipid and protein form part of the surface of the virion, which is known as the surface antigen HBsAg...

Hepatitis B virus is a member of the Hepadnavirus family. Virion diameter of this virus is 22 nm. Lipid and protein form part of the surface of the virion, which is known as the surface antigen HBsAg...

HBX-41108 is a potent inhibitor of ubiquitin-specific protease (USP) 7 activity (IC₅₀ = 424 nM). Also inhibits USP7-mediated p53 deubiquitination (IC₅₀ = 0.8 μM). HBX-41108 treatment stabilizes p53,...

HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize. It is a reversible inhibitor of histone deacetylases (HDACs) (IC₅₀ = 30 nM). Through its...

3393 | HCAM Antibody DataSheet

3393BP | HCAM Blocking Peptide DataSheetAntibody Target: HCAM Accession #: P16070Gene ID: 960Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

Human HerpatoCellular Carcinoma (HCC-1) was first isolated from the hemofiltrate of patients with chronic renal failure. HCC-1 has a 46% amino acid sequence identity with MIP-1 /MIP-1 and 29%-37%...

HCK, a protein-tyrosine kinase, belongs to SRC family members (1). Ziegler et al. found that expression of HCK may be limited to certain hemopoietic cells and is especially prominent in cells of...

K1310 | HCV Maxi Purification Kit DataSheet

K1309 | HCV Mini Purification Kit DataSheet

K331 | HDAC Activity Colorimetric Assay Kit DataSheet

K330 | HDAC Activity Fluorometric Assay Kit DataSheet

K333 | HDAC Family Antibody Set DataSheet

A colorimetric substrate for histone deacetylases (HDACs). Cleavage of pNA is monitored colorimetrically at ~405 nm.HDAC substrate II is a colorimetric substrate for histone deacetylases (HDACs)...

A colorimetric substrate for histone deacetylases (HDACs).A colorimetric substrate for histone deacetylases (HDACs).2207 | HDAC Substrate, Colorimetric DataSheetAlternate Name/Synonyms: Boc-...

A useful fluorometric substrate for histone deacetylases (HDACs). Ex(max): 330nm; Em(max): 395nm.HDAC substrate, fluorogenic is a useful substrate for histone deacetylases (HDACs).2396 | HDAC...

HDAC, EGFR, and HER2 Inhibitor is a multitargeted inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) with IC₅₀ values...

3601BP | HDAC-1 Blocking Peptide DataSheetAntibody Target: HDAC-1 Accession #: NP_004955Gene ID: 3065Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3610BP | HDAC-10 Blocking Peptide DataSheetAntibody Target: HDAC-10 Accession #: AAL30513Gene ID: 83933Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3611BP | HDAC-11 Blocking Peptide DataSheetAntibody Target: HDAC-11 Accession #: Q96DB2Gene ID: 79885Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: In phosphate buffered saline...

3602BP | HDAC-2 Blocking Peptide DataSheetAntibody Target: HDAC-2 Accession #: EAW48255Gene ID: 3066Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3603BP | HDAC-3 Blocking Peptide DataSheetAntibody Target: HDAC-3 Accession #: NP_003874Gene ID: 8841Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

Human Histone Deacetylase 3 (HDAC3) is a member of the class I Histone Deacetylases. HDACs are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. HDACs...

3604BP | HDAC-4 Blocking Peptide DataSheetAntibody Target: HDAC-4 Accession #: NP_006028 Gene ID: 9759Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3605BP | HDAC-5 Blocking Peptide DataSheetAntibody Target: HDAC-5 Accession #: Q9UQL6Gene ID: 10014Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K171 | HDAC-5 Inhibitor Screening Kit Fluorometric DataSheet