PAX2 Antibody| F45252-0.08ML/F45252-0.4ML/R32185/V7450-20UG

PAX2 Antibody| F45252-0.08ML/F45252-0.4ML/R32185/V7450-20UG | Gentaur UK, US & Europe Distribution

Background: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the PAX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This PAX2 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 187-216 from the human protein was used as the immunogen for this PAX2 antibody.

Storage: Aliquot the PAX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A