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- Product
- Qty in Cart
- Quantity
- Price
- Subtotal
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JARID2 polyclonal antibody | 6856
26
zł2,916.006856 | JARID2 polyclonal antibody DataSheet26-6856-50-GENzł2,916.00 -
Jasplakinolide, jaspis johnstoni | 1689
26
zł3,108.00A cell- permeable, non-fluorescent F-actin probe. Displays antifungal and antitumor properties. A potent inducer of actin polymerization and stabilization, Jasplakinolide competes with phallotoxins...26-1689-GENzł3,108.00 -
Jatrorrhizine | 2530
26
zł4,386.00Jatrorrhizine is a a novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb coptidis rhizome. Protects neuronal-like cells against H₂O₂-induced toxicity. JAT also displays...26-2530-GENzł4,386.00 -
JC-1 | 1130
26
zł3,798.00JC-1 is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-1 monomer is in equilibrium with so called J-aggregates, which are favored at higher...26-1130-GENzł3,798.00 -
JE (MCP-1), murine recombinant | 4207
26
zł2,868.00 - zł28,122.00Murine JE (also known as Macrophage/Monocyte Chemotactic Protein) is a 13.8 kDa protein containing 125 amino acid residues. It plays an important role in the inflammatory response of blood monocytes...26-4207-GENzł2,868.00 - zł28,122.00 -
Jervine | 2357
26
zł2,328.00 - zł5,862.00Cell-permeable. Structurally similar to cyclopamine (Cat. No. 1578). Inhibits the sonic hedgehog (shh) pathway by interacting with smoothened. Jervine can be used to induce abnormal morphogenesis in...26-2357-GENzł2,328.00 - zł5,862.00 -
JFD00244 | B2830
26
zł1,638.00 - zł2,520.00JFD00244 is an inhibitor of SIRT2. SIRT2 is a NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase. A major substrate of SIRT2 is α-tubulin. JFD00244 inhibits SIRT2 with an IC₅₀ of 56.7 µM...26-B2830-GENzł1,638.00 - zł2,520.00 -
JGB1741 | B2804
26
zł2,034.00 - zł4,686.00JGB1741 is a small molecule inhibitor of SIRT1. The sirtuins (SIRTs) are NAD+-dependent histone deacetylases. The IC₅₀ value of JGB1741 in a cell-free assay is 15 μM. The IC₅₀ for cell proliferation...26-B2804-GENzł2,034.00 - zł4,686.00 -
JH-II-127 | 9632
26
zł2,328.00 - zł5,964.00JH-II-127 is a highly potent, selective, and cell-permeable LRRK2 inhibitor, with IC₅₀ of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T. JH-II-127 substantially inhibits...26-9632-GENzł2,328.00 - zł5,964.00 -
zł4,488.00
-
zł1,974.00
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JIP-1 Blocking Peptide | 3664BP
26
zł2,034.003664BP | JIP-1 Blocking Peptide DataSheetAntibody Target: JIP-1 Accession #: Q9WVI9Gene ID: 19099Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...26-3664BP-50-GENzł2,034.00 -
JK 184 | 1726
26
zł2,124.00An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Aldh7) (IC₅₀ = 210 nM).JK...26-1726-GENzł2,124.00 -
zł4,488.00
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JM6 | 1913
26
zł5,178.00Cell-permeable. A slow-release prodrug version of Ro 61-8048 (Cat. No. 1912-5, 25), an inhibitor of KMO (kynurenine 3-monoxygenase), the enzyme that controls the kynurenine pathway, long believed to...26-1913-GENzł5,178.00 -
JMJ1DC Blocking peptide | 3439BP
26
zł2,034.003439BP | JMJ1DC Blocking peptide DataSheetAntibody Target: JMJ1DCAccession #: Q15652Gene ID: 221037Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...26-3439BP-50-GENzł2,034.00 -
zł1,974.00
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JMJD1A Blocking Peptide | 3273BP
26
zł2,034.003273BP | JMJD1A Blocking Peptide DataSheetAntibody Target: JMJD1AAccession #: Q9Y4C1Gene ID: 55818Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...26-3273BP-50-GENzł2,034.00 -
zł1,974.00
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zł3,108.00
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JMJD2a polyclonal antibody | 6851
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zł2,916.006851 | JMJD2a polyclonal antibody DataSheet26-6851-25-GENzł2,916.00 -
JMJD2b polyclonal antibody | 6852
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zł4,002.006852 | JMJD2b polyclonal antibody DataSheet26-6852-50-GENzł4,002.00 -
JMJD2c polyclonal antibody | 6853
26
zł2,916.006853 | JMJD2c polyclonal antibody DataSheet26-6853-50-GENzł2,916.00 -
zł3,312.00
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JNJ-10198409 | B1078
26
zł7,488.00JNJ-10198409 is a potent, cell-permeable, ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenic and a direct tumor cell...26-B1078-GENzł7,488.00 -
JNJ-1661010 | 2413
26
zł4,782.00Cell-permeable. A potent , selective and reversible FAAH (Fatty Acid Amide Hydrolase) inhibitor. Initially forms a covalent adduct with FAAH but is slowly released, IC₅₀ = 12 nM. Displays100-fold...26-2413-GENzł4,782.00 -
JNJ-17203212 | B2974
26
zł3,162.00 - zł9,348.00JNJ-17203212 is a reversible and potent antagonist of transient receptor potential vanilloid 1 (TRPV1) with pKi values of 6.5, 7.1 and 7.3 at rat, guinea pig and human TRPV1 respectively. It Inhibits...26-B2974-GENzł3,162.00 - zł9,348.00 -
JNJ-26481585 | 9612
26
zł7,488.00JNJ-26481585 is a second-generation pyrimidyl-hydroxamic acid histone deacetylase (HDAC) inhibitor with high cellular potency towards Class I and II HDACs. It displays potent antineoplastic...26-9612-GENzł7,488.00 -
JNJ-26854165 | 2479
26
zł4,002.00A novel p53-activating tryptamine derivative that acts as a HDM2 (Human Double Minute-2) antagonist with potential antineoplastic activity. JNJ-26854165 inhibits the binding of the HDM2–p53 complex...26-2479-GENzł4,002.00 -
JNJ-27018966 | B1109
26
zł2,328.00JNJ-27018966 is an orally active μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist, with powerful antidiarrheal and analgesic activity. It is believed to act locally in the enteric...26-B1109-GENzł2,328.00 -
JNJ-31020028 | 9648
26
zł2,328.00 - zł5,964.00JNJ-31020028 is a selective brain -penetrant small molecule antagonist of the neuropeptide Y2 (NPY2) receptor.JNJ-31020028 is a selective brain -penetrant small molecule antagonist of the...26-9648-GENzł2,328.00 - zł5,964.00 -
JNJ-38877605 | B2063
26
zł2,724.00 - zł7,488.00JNJ-38877605 is a potent c-MET tyrosine kinase inhibitor with potential anti-neoplastic activity. It is potent (IC₅₀ values of 4 nM and 50 nM for c-MET enzyme and Phospho-MET respectively). Displays...26-B2063-GENzł2,724.00 - zł7,488.00 -
JNJ-42041935 | B1072
26
zł2,226.00 - zł5,568.00JNJ-42041935 is a HIF-PHD (Hypoxia-inducible factor- prolyl hydroxylase) inhibitor. JNJ-42041935 is a selective, 2-OG (2-oxoglutarate) competitive, and reversible inhibitor of PHD enzymes (pKis = 7...26-B1072-GENzł2,226.00 - zł5,568.00 -
JNJ-47965567 | B2972
26
zł2,328.00 - zł5,964.00JNJ-47965567 is a potent and selective antagonist of the purinergic receptor P2X subtype 7 (P2X7), a ligand-gated ion channel. Activation of P2X receptors by BzATP induces calcium flux. JNJ-47965567...26-B2972-GENzł2,328.00 - zł5,964.00 -
JNJ-64619178 | B3322
26
zł2,328.00 - zł5,964.00JNJ-64619178 is a selective and pseudo-irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50 of 0.14 nM). It inhibits the growth of various cancer cells in vitro and reduces tumor...26-B3322-GENzł2,328.00 - zł5,964.00 -
JNJ-7706621 | B1941
26
zł1,932.00 - zł4,386.00JNJ-7706621 is a potent inhibitor of cyclin-dependent kinases (CDK) and Aurora kinases with IC₅₀ values of 9 nM, 4 nM, 11 nM and 15 nM for CDK1, 2 and Aurora A, B, respectively. In vitro assays shows...26-B1941-GENzł1,932.00 - zł4,386.00 -
JNK Activated Cell Lysate | 7032
26
zł3,504.00Jurkat cells are cultured in RPMI medium supplement with 10% FBS. The cells were grown to late growing phase. Anisomycin is added to the medium to a final concentration 10 µg/ml ( cat# 1549-10,...26-7032-GENzł3,504.00 -
JNK Activity Assay Kit, KinaseSTAR - K431
26
zł6,654.00K431 | JNK Activity Assay Kit, KinaseSTAR DataSheet26-K431-40-GENzł6,654.00 -
JNK Activity Screening Kit, KinaseSTAR - K430
26
zł6,018.00K430 | JNK Activity Screening Kit, KinaseSTAR DataSheet26-K430-40-GENzł6,018.00 -
zł1,974.00
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JNK Blocking Peptide | 3701BP
26
zł2,034.003701BP | JNK Blocking Peptide DataSheetAntibody Target: JNK Accession #: P45983Gene ID: 5599Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...26-3701BP-50-GENzł2,034.00 -
JNK Negative Control Cell Lysate | 7031
26
zł3,504.00The cell Lysate prepared from uninduced Jurkat cells can be used as a negative control for JNK activity assays in conjunction with ’s JNK Activity Assay Kit (K430-40 or K431-40). We recommend using...26-7031-GENzł3,504.00 -
JNK-IN-7 | B1695
26
zł2,328.00 - zł5,964.00JNK-IN-7 is a selective JNK inhibitor with IC50 values of 1.54 nM, 1.99 nM, 0.75 nM to JNK1, JNK2, JNK3, respectively. It also inhibits phosphorylation of c-Jun, which is a direct substrate of JNK...26-B1695-GENzł2,328.00 - zł5,964.00 -
JNK-IN-8 | 2729
26
zł2,622.00 - zł23,400.00JNK-IN-8 is a potent and irreversible JNK inhibitor that inhibits the phosphorylation of c-Jun. It inhibits JNK1, JNK2 and JNK4 with IC₅₀ values of of 4.7 nM, 18.7 nM and 1 nM, respectively.JNK-IN-8...26-2729-GENzł2,622.00 - zł23,400.00 -
JNK1, Active | 7757
26
zł4,002.00 - zł39,918.00JNK1 is a member of the MAP kinase group that is activated by dual phosphorylation at thr and tyr residues during exposure to stress such as UV irradiation. JNK1 binds to the c-Jun transactivation...26-7757-GENzł4,002.00 - zł39,918.00 -
JTE-607 | B3064
26
zł2,328.00 - zł5,964.00JTE-607 is a multiple cytokine inhibitor. It inhibits cytokine production specifically in human peripheral blood mononuclear cells without causing immunosuppression. It inhibits tumor necrosis...26-B3064-GENzł2,328.00 - zł5,964.00 -
Jumonji HDM Inhibitor, JIB-04 | 2474
26
zł4,782.00JIB-04 (E-isomer) is a potent, cell-permeable inhibitor of Jumonji histone demethylases in vitro and in vivo. (In vitro IC₅₀ values are 230, 340, 435, 445, 855 and 1100 nM for JARID1A, JMJD2E,...26-2474-GENzł4,782.00 -
Jumonji HDM Inhibitor, PBIT | 2475
26
zł6,504.00PBIT is a potent, cell-permeable inhibitor of Jumonji histone demethylase (JHDM). Innhibits JARID1B (also known as KDM5B or PLU1) with an IC₅₀ of about 3 μm in vitro. PBIT treatment inhibits removal...26-2475-GENzł6,504.00 -
Jurkat Cell Extract (Induced) | 1107
26
zł3,504.00The cytosolic extract was prepared from Jurkat cells induced with 2 µM camptothecin. The extract can be used as a positive control for caspase activity assays or for Western blotting. We recommend...26-1107-GENzł3,504.00 -
Jurkat Cell Extract (Uninduced) | 1106
26
zł3,312.00The cytosolic extract prepared from uninduced Jurkat cells can be used as a control for caspase activity assays or for Western blotting. We recommend using 100-200 µg per assay for caspase activity...26-1106-GENzł3,312.00 -
Jurkat cell Lysate (Camptothecin-treated) | 2402
26
zł2,328.00Jurkat cells were treated with 2 mM camptothecin for 6 hours. Cell lysate was prepared by homogenization in modified RIPA buffer (150 mM NaCl, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic...26-2402-GENzł2,328.00 -
Jurkat cell Lysate (untreated) | 2401
26
zł2,328.00The Jurkat cell lysate was prepared by homogenization in modified RIPA buffer (150 mM NaCl, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl flouride, 1% Triton...26-2401-GENzł2,328.00 -
JW55 | 2612
26
zł4,242.00JW55 is a small molecule inhibitor of the Wnt/β-catenin signaling pathway that functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2), regulators of the β-catenin...26-2612-GENzł4,242.00 -
JWH-250 Synthetic Cannabinoid Antibody | 6206
26
zł3,708.006206 | JWH-250, Synthetic Cannabinoid Antibody DataSheet26-6206-200-GENzł3,708.00 -
JZL-184 | B2755
26
zł2,226.00 - zł5,568.00JZL-184 is a potent and selective inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 8 nM and 4 µM for inhibition of MAGL and fatty acid amide hydrolase in mouse brain...26-B2755-GENzł2,226.00 - zł5,568.00 -
JZL195 | B1064
26
zł1,932.00 - zł4,386.00JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) (IC₅₀ = 2 nM) and fatty acid amide hydrolase (FAAH) (IC₅₀ = 4 nM), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol...26-B1064-GENzł1,932.00 - zł4,386.00 -
K-604, ACAT-1 Inhibitor | B2926
26
zł2,520.00 - zł6,744.00K-604 is an inhibitor of acyl-CoA:cholesterol acyltransferase 1 (ACAT1). The IC₅₀ values of K-604 for human ACAT-1 and ACAT-2 are 0.45 μM and 102.85 μM respectively, showing that K-604 is 229-fold...26-B2926-GENzł2,520.00 - zł6,744.00 -
K-7174 dihydrochloride | 9478
26
zł6,744.00K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α. K7174 also ameliorated anemia...26-9478-GENzł6,744.00 -
K-777 | B3329
26
zł2,034.00 - zł4,782.00K-777 is a potent and irreversible cysteine protease inhibitor. Also acts as a potent cysteine protease cruzain (cruzipain) inhibitor. Active against Trypanosoma cruzi the causative agent of Chagas'...26-B3329-GENzł2,034.00 - zł4,782.00 -
K02288 | B2321
26
zł2,034.00 - zł4,782.00A potent and selective inhibitor of type I bone morphogenic protein (BMP) receptors (IC₅₀ values are 1.1, 1.8, 6.4, 34.4, 220, 302 and 321 nM for ALK2, ALK1, ALK6, ALK3, ActRIIA, ALK4 and ALK5...26-B2321-GENzł2,034.00 - zł4,782.00 -
K11-linked Di-Ubiquitin | 6421
26
zł3,606.00Increasingly, researchers are focusing on the role poly-ubiquitin chains linked through K11. This post-translational modification has been linked to the ERAD cycle as a signal, similar to K48...26-6421-GENzł3,606.00 -
K11-linked Tetra-Ubiquitin | 6423
26
zł5,712.00Increasingly, researchers are focusing on the role poly-ubiquitin chains linked through K11. This post-translational modification has been linked to the ERAD cycle as a signal, similar to K48...26-6423-GENzł5,712.00 -
K11-linked Tri-Ubiquitin | 6422
26
zł3,606.00Increasingly, researchers are focusing on the role poly-ubiquitin chains linked through K11. This post-translational modification has been linked to the ERAD cycle as a signal, similar to K48...26-6422-GENzł3,606.00 -
K2/spice Synthetic Cannabinoids Antibody | 6205
26
zł3,708.006205 | K2/spice, Synthetic Cannabinoids Antibody DataSheet26-6205-200-GENzł3,708.00 -
K252a | 2013
26
zł2,472.00An analog of Staurosporine (Cat. No. 1048) that acts as a non-selective protein kinase inhibitor. Iinhibits PKA (Ki = 18 nM), PKC (Ki = 25 nM), and PKG (Ki = 20 nM). Potently inhibits CaMK (Ki = 1.8...26-2013-GENzł2,472.00 -
K48-linked Di-Ubiquitin | 6415
26
zł2,376.00Poly-ubiquitylation of target proteins through linkage at K48, is now the most thoroughly studied of the various chain linkages, and was once considered the hallmark of this post-translational...26-6415-GENzł2,376.00 -
K48-linked Tetra-Ubiquitin | 6417
26
zł4,002.00Poly-ubiquitylation of target proteins through linkage at K48, is now the most thoroughly studied of the various chain linkages, and was once considered the hallmark of this post-translational...26-6417-GENzł4,002.00 -
K48-linked Tri-Ubiquitin | 6416
26
zł3,606.00Poly-ubiquitylation of target proteins through linkage at K48, is now the most thoroughly studied of the various chain linkages, and was once considered the hallmark of this post-translational...26-6416-GENzł3,606.00 -
K63-linked Di-Ubiquitin | 6418
26
zł3,750.00Poly-ubiquitination of target proteins through K63 has recently become the focus of intense study. The topology of this linkage type is quite different from polyubiquitin linked through lysine 48. ...26-6418-GENzł3,750.00 -
K63-linked Tetra-Ubiquitin | 6420
26
zł4,002.00Poly-ubiquitination of target proteins through K63 has recently become the focus of intense study. The topology of this linkage type is quite different from polyubiquitin linked through lysine 48. ...26-6420-GENzł4,002.00 -
K63-linked Tri-Ubiquitin | 6419
26
zł3,750.00Poly-ubiquitination of target proteins through K63 has recently become the focus of intense study. The topology of this linkage type is quite different from polyubiquitin linked through lysine 48. ...26-6419-GENzł3,750.00 -
K858 | B1073
26
zł2,418.00K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC₅₀ = 1.3 µM) and an antitumor agent. Induces cell death in cancer cells, blocks centrosome separation, activates the spindle...26-B1073-GENzł2,418.00 -
Kaempferol | 2523
26
zł1,932.00 - zł4,386.00A naturally occurring polyphenol antioxidant that displays a wide range of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, cardioprotective,...26-2523-GENzł1,932.00 - zł4,386.00 -
Kainic acid | 2279
26
zł1,932.00 - zł4,092.00A conformationally restricted glutamate analog that acts as a selective agonist at kinate receptors. A CNS stimulant and neurotoxin. Classic neuroexcitatory agent for induction of seizures in...26-2279-GENzł1,932.00 - zł4,092.00 -
Kallikrein 12 (KLK12) Blocking Peptide | 3720BP
26
zł2,034.003720BP | Kallikrein 12 (KLK12) Blocking Peptide DataSheetAntibody Target: Kallikrein 12 (KLK12) Accession #: AAH35385.1Gene ID: 43849Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation:...26-3720BP-50-GENzł2,034.00 -
Kallikrein 12 KLK12 Antibody | 3720
26
zł1,974.003720 | Kallikrein 12 (KLK12) Antibody DataSheet26-3720-30T-GENzł1,974.00 -
Kallikrein, Human Plasma | 4093
26
zł3,108.00A serine protease that releases bradykinin from kininogen. Present in plasma as an inactive precursor prokallikrein.4093 | Kallikrein Human Plasma DataSheetBiomolecule/Target: KallikreinSynonyms:...26-4093-GENzł3,108.00 -
Kallikrein-2, Human Recombinant | P1579
26
zł2,124.00 - zł5,568.00KLK2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array...26-P1579-GENzł2,124.00 - zł5,568.00 -
Kallistatin Human Elisa Kit - E4279
26
zł8,124.00E4279 | Kallistatin Human Elisa Kit DataSheet26-E4279-100-GENzł8,124.00 -
zł8,466.00
-
Kanamycin Sulfate, USP | 2498
26
zł5,766.00Kanamycin, USP is an aminoglycoside antibiotic often used to select for bacteria which have been successfully transformed with a plasmid conferring kanamycin resistance. Kanamycin interacts with the...26-2498-GENzł5,766.00 -
zł3,504.00
-
Kartogenin | 2066
26
zł1,986.00 - zł4,632.00Cell-permeable. Kartogenin promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC₅₀ = 100 nM). Displays chondroprotective effects in vitro and is...26-2066-GENzł1,986.00 - zł4,632.00 -
kb NB 142-70 | 9566
26
zł2,724.00 - zł7,488.00kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC₅₀ values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively. More potent analog of CID-755673 (Cat.No. 2660) with 7-fold...26-9566-GENzł2,724.00 - zł7,488.00 -
zł4,050.00
-
KC Blocking Peptide | 5212BP
26
zł2,034.005212BP | KC Blocking Peptide DataSheetAntibody Target: KC Accession #: AAH37997Gene ID: 14825Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...26-5212BP-50-GENzł2,034.00 -
KC7F2 | 9641
26
zł2,034.00 - zł4,782.00KC7F2 is a small molecule HIF-1 pathway inhibitor that inhibits HIF-1α protein translation, but not transcription. It inhibits hypoxia-induced expression of several HIF target genes, such as carbonic...26-9641-GENzł2,034.00 - zł4,782.00 -
KD 5170 | B2820
26
zł1,740.00 - zł3,504.00KD 5170 is a broad spectrum, classes I and II HDAC (histone deacetylase) inhibitor. The IC₅₀ for inhibition of HDAC1, HDAC2, HDAC3, HDAC4 is 0.02 μM, 2 μM, 0.075 μM, 0.026 μM respectively, in vitro...26-B2820-GENzł1,740.00 - zł3,504.00 -
KDM1B polyclonal antibody | 6847
26
zł2,916.006847 | KDM1B polyclonal antibody DataSheet26-6847-50-GENzł2,916.00 -
Kenpaullone | 1904
26
zł1,884.00Cell-permeable. A potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with much less effect other kinases. In addition, it has been found to be a...26-1904-GENzł1,884.00 -
Keratin-8, human recombinant | 4817
26
zł7,038.00Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is...26-4817-GENzł7,038.00 -
Ketoconazole | B2735
26
zł1,740.00 - zł3,018.00Ketoconazole is a broad-spectrum triazole antifungal agent. It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase, which arrests ergosterol biosynthesis...26-B2735-GENzł1,740.00 - zł3,018.00 -
Ketorolac | B2170
26
zł1,638.00 - zł3,018.00Ketorolac is a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic, and antipyretic activities. Ketorolac non-selectively inhibits the enzymes COX-1 and COX-2. The...26-B2170-GENzł1,638.00 - zł3,018.00 -
Kevetrin hydrochloride | B1068
26
zł1,932.00Kevetrin is a water-soluble, small molecule activator of the tumor suppressor protein p53, with potential antineoplastic activity. p53 functions by activating proteins that repair DNA and kill cells...26-B1068-GENzł1,932.00 -
KG-501 | B2380
26
zł2,034.00 - zł4,782.00KG-501 is a cAMP response element-binding protein (CREB) inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM).KG-501 is a cAMP response...26-B2380-GENzł2,034.00 - zł4,782.00 -
zł1,974.00
-
KH7 | 2350
26
zł5,766.00A selective inhibitor of soluble adenylyl cyclase (sAC) ( IC₅₀ = 3-10 µM in vivo). Displays little effect on transmembrane adenylyl cyclases. KH7 is not active against sAC in the presence of...26-2350-GENzł5,766.00 -
KHS-101 | B2415
26
zł5,964.00KHS-101 is a selective inducer of neuronal differentiation. It induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Also...26-B2415-GENzł5,964.00 -
Ki 16425 | 9545
26
zł5,568.00Ki 16425 is a LPA (Lysophosphatidic acid) receptor antagonist with selectivity for LPA1 and LPA3. It exhibits Ki values of 0.34, 6.5, and 0.93 µM for the human LPA1, LPA2, and LPA3 receptors,...26-9545-GENzł5,568.00 -
Ki 8751 | 2677
26
zł4,002.00Ki 8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC₅₀ = 0.9 nM). It is >40-fold selective for VEGFR2 than c-Kit, PDGFRα and FGFR-2, little activity to EGFR, HGFR and InsR.Ki 8751...26-2677-GENzł4,002.00